Postoperative Pain Clinical Trial
Official title:
Efficacy and Tolerance of Parecoxib for Prevention of Catheter-related Bladder Discomfort in Patients Undergoing Catheterization After TURBT: A Prospective, Randomized, Placebo-controlled, Double-blind Study
Catheter-related bladder discomfort (CRBD) is defined as an urge to void or discomfort in the supra-pubic region; reported postoperatively in patients who have had urinary catheterization intra-operatively. In the present study, the investigators evaluated Parecoxib (P) for preventing CRBD in patients undergoing catheterization after transurethral resection of bladder tumor (TURBT).
Participants will be randomized into one of two study groups: Group P: 40 mg of intravenous
parecoxib 30 min before surgery and Control Group C: an equal volume of saline.
Lumber subarachnoid block was administered with 2 ml 0.5% hyperbaric bupivacaine and 2.5 µg
Sufentanyl. Intra-operatively, urinary catherization was performed with a 16 Fr Foley's
catheter, and the balloon was inflated with 10 ml distilled water. The CRBD was assessed at
0, 1, 2, and 6 h after patient's arrival in the post-anaesthesia care unit. Severity of CRBD
was graded as none, mild, moderate and severe.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Prevention
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