Quadratus Lumborum Block for Postoperative Analgesia After Colostomy Closure

Postoperative Pain Clinical Trial

Official title:

Ultrasound-guided Quadratus Lumborum Block for Postoperative Analgesia After Colostomy: A Randomized Controlled Trial

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT02691403
• Other study ID #: QLCO
• Status: Not yet recruiting
• Phase: Phase 4
• First received: February 17, 2016
• Last updated: February 21, 2016
• Start date: March 2016

Study information

• Verified date: February 2016
• Source: Sun Yat-sen University
• Contact: n/a
• Is FDA regulated: No
• Health authority: Taiwan: Ministry of Health and Welfare
• Study type: Interventional

Clinical Trial Summary

Patients undergoing abdominal procedures often require multimodal postoperative pain controls. Truncal blocks such as quadratus lumborum (QL) block may be used adjunctively as a part of it. The investigators hypothesized that the ultrasound-guided QL block with transmuscular approach can provide adequate pain relief for colostomy closure as part of a multimodal pain control.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 50
• Est. primary completion date: June 2017
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 20 Years to 75 Years

Eligibility

Inclusion Criteria:

• A physical status between ASA I and III

• 20 - 75 years of age

• Patient has signed an informed consent

• Without contraindication of QL block

Exclusion Criteria

• American Society of Anesthesiologists (ASA) Physical Status = 4

• Any contraindication to nerve blocks (including coagulopathy, abnormal anatomy, infection at the planned QL injection site, and amide-type local anesthetic allergy) pregnancy or breast-feeding

• Severe obesity (body mass index= 35 kg/m2)

• Patients with a history of significant neurological, psychiatric, neuromuscular, cardiovascular, pulmonary, renal or hepatic disease

• Allergy to NSAIDs

• Infection at the QL injection site

• Patients with major psychosis or drug and alcohol abuse

• Patient unable to comprehend or use the verbal rating pain scoring system or patient-controlled analgesia pump

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Pain, Postoperative
• Postoperative Pain

Intervention

Drug:
• levo-bupivacaine

• normal saline

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Sun Yat-sen University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	cumulative morphine consumption		1 hour	No