Postoperative Pain Clinical Trial
Official title:
Intraoperative Wound Infiltration With Local Anaesthetic in Surgical Patients; Is There Any Late Effect on the Postoperative Pain and the Requirements of Analgesia ? A Randomized Control Trial.
Background: Intraoperative wound infiltration with local anaesthetic is commonly used. Apart
from the obvious immediate action it has been supported that a possible down regulation of
pain receptors may lead to longer effects. Our aim was to compare the use of local
anaesthetic versus placebo in order to assess if indeed there is a late beneficial effect.
Materials and methods: We will conduct a RCT involving 400 consecutive general surgery
patients randomized in 2 groups: Group A= placebo, Group B= wound infiltration with
ropivacaine 10%. We will record the preoperative and postoperative pain for the 1st week as
well as the type and quantity of the analgesia used during the study period.
Hypothesis : patients who receive intraoperatively wound infiltration with local anaesthetic
have lower pain during the 1st postoperative week and require less pain killers .
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
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