Postoperative Pain Clinical Trial
Official title:
Comparison of Intravenous Lidocaine and Intraperitoneal Lidocaine Irrigation for Effective Pain Relief After Laparoscopic Cholecystectomy: A Prospective, Randomized, Double-blind, Placebo-controlled Study
This prospective randomized study aims to comparison the effectiveness of intravenous
lidocaine injection and intraperitoneam lidocaine irrigation on the relief of pain in
patients undergoing laparoscopic cholecystectomy.
A total of 83 patients will be randomized into one of three groups (group C or group I or
group P) based on Excel number generation.
Patients in group C will receive normal saline intravenous injection, and patients in group
I will receive an intravenous bolus injection of 1.5 mg/kg lidocaine followed by a
continuous lidocaine infusion of 2 mg/kg/hr.
Patients in group P will receive intraperitoneal lidocaine irrigation with 3.5 mg/kg
lidocaine and normal saline 100cc.
Visual analogue scale pain scores, fentanyl consumption and the frequency at which patients
pushed the button (FPB) of a patient-controlled analgesia system will be recorded at 2, 4,
8, 12, 24, 48 hours postoperatively.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment
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