Postoperative Pain Clinical Trial
Official title:
Analgesic Effect of Perioperative Escitalopram for Patients With High Preoperative Level of Pain Catastrophising in Total Knee Arthroplasty
Pain is a major problem after TKA, especially in patients with high pain catastrophizing. Newer MR-scan studies indicate that Escitalopram may have an immediate cognitive and emotional effect. The investigators therefore investigate the effect of Escitalopram as a perioperative analgesic.
Pain is a major problem after TKA, especially in patients with high pain catastrophizing.
Newer MR-scan studies indicate that Escitalopram may have an immediate cognitive and
emotional effect. Patients with high pain catastrophizing are mentally vulnerable and may be
sensitive to the effects of Escitalopram.
We therefore investigate the effect of Escitalopram as a perioperative analgesic in this
group of patients where the pain problem is pronounced.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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