Postoperative Pain Clinical Trial
Official title:
The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Revision Knee Arthroplasty
The purpose of this study is to determine whether Adductor-Canal-Blockade is effective at reducing pain and morphine consumption after revision knee arthroplasty.
Status | Completed |
Enrollment | 36 |
Est. completion date | April 2013 |
Est. primary completion date | April 2013 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 40 Years to 85 Years |
Eligibility |
Inclusion Criteria: - Revision Knee Arthroplasty in general anaesthesia - American society of anesthesiologists (ASA) 1-3 - BMI 18-40 - Written informed consent Exclusion Criteria: - Can not cooperate to the exam - Do not speak or understand Danish - Drug allergy - Alcohol or drug abuse |
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Denmark | Department of Anaesthesia and Surgery, HOC, Rigshospitalet, Denmark | Copenhagen | København Ø |
Lead Sponsor | Collaborator |
---|---|
Rigshospitalet, Denmark |
Denmark,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Pain during 45 degrees active flexion of the knee | 0-100 mm at a visual analogue scale (VAS), at 4 hours postoperative. | 4 hours postoperative | No |
Secondary | Pain during 45 degrees active flexion of the knee | 0-100 mm at a visual analogue scale (VAS), registered at the intervals 1, 2, 4, 6 and 8 hours postoperative, calculated as "the area under the curve" (AUC) for the interval 1-8 hours postoperative. | 1-8 hours postoperative | No |
Secondary | Pain during 45 degrees active flexion of the knee | 0-100 mm at a visual analogue scale (VAS), at 24 hours postoperative. | 24 hours postoperative | No |
Secondary | Pain during rest | 0-100 mm at a visual analogue scale (VAS), registered at the intervals 1, 2, 4, 6 and 8 hours postoperative, calculated as "the area under the curve" (AUC) for the interval 1-8 hours postoperative. | 1-8 hours postoperative | No |
Secondary | Pain during rest | 0-100 mm at a visual analogue scale (VAS), at 24 hours postoperative. | 24 hours postoperative | No |
Secondary | Total morphine consumption | Total morphine consumption at the intervals 0-8, 8-24 and 0-24 hours postoperative. | 0-24 hours postoperative | No |
Secondary | Postoperative nausea | Nausea scores(0-3)registered at 1,2,4,6 and 8 hours postoperative, calculated as mean value for the interval 1-8 hours postoperative. | 1-8 hours postoperative | No |
Secondary | Postoperative nausea | Nausea score(0-3)at 24 hours postoperative. | 24 hours postoperative | No |
Secondary | Postoperative vomiting | Number of vomiting episodes at the intervals 0-8, 8-24 and 0-24 hours postoperative. | 0-24 hours postoperative | No |
Secondary | Zofran consumption | Total zofran consumption at the intervals 0-8, 8-24 and 0-24 hours postoperative. | 0-24 hours postoperative | No |
Secondary | Sedation | Sedation score (0-3) registered at 1,2,4,6 and 8 hours postoperative, calculated as the mean value for the interval 1-8 hours postoperative. | 1-8 hours postoperative | No |
Secondary | Sedation | Sedation score (0-3) at 24 hours postoperative. | 24 hours postoperative | No |
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