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Postoperative Pain clinical trials

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NCT ID: NCT03490006 Withdrawn - Postoperative Pain Clinical Trials

Erector Spinae Plane Block Versus Paravertebral Block in Mastectomy

Start date: August 2018
Phase: Phase 4
Study type: Interventional

In this randomized, controlled, observer-blinded study the investigators plan to evaluate ultrasound-guided thoracic paravertebral block (TPVB) and ultrasound-guided thoracic erector spinae plane (TESP) block for postoperative pain management after unilateral total mastectomy without immediate reconstruction.

NCT ID: NCT03369782 Withdrawn - Surgery Clinical Trials

Effect of NMBA on Surgical Conditions in THR

Start date: December 15, 2017
Phase: Phase 4
Study type: Interventional

During Total hip replacement arthroplasty (THA), the hip joint first must be luxated in order to have access to the joints. A lot of force and torque must be carried out on the joint to perform this manipulation. This is both difficult for the surgeon and may cause additional tissue damage and postoperative pain. After placement of the prosthesis and reduction of the joint, the tension of the hip joint must be evaluated by the surgeon to ascertain the adequacy of the prosthesis. During luxation, minimal muscle tension would be ideal, while after reduction of the joint, normal muscle tension is desired to permit assessment of the mechanics of the hip joint. The aim of the study is to investigate whether deep neuromuscular block, combined with a reversal before mechanics assessment improves surgical conditions, surgical time, and postoperative patient comfort.

NCT ID: NCT03058354 Withdrawn - Postoperative Pain Clinical Trials

Study to Investigate TIVA With Propofol on Postoperative Pain and Side Effects

Start date: January 1, 2017
Phase:
Study type: Observational

Propofol is a commonly used anaesthetic with rapid recovery and less side effects and total intravenous anaesthesia (TIVA) with propofol is a common technique now. The reduction on certain serum pro- inflammatory cytokines may lead to more smooth post- surgical recovery. Recent case report proved the analgesic effect of propofol infusion. However other animal and clinical studies showed controversial result. The aim of this retrospective study is to investigate the postoperative analgesic effects and side effects of intraoperative TIVA with propofol in patient undergoing surgery at Queen Mary Hospital, Hong Kong between 2014 to 2016.

NCT ID: NCT03043027 Withdrawn - Postoperative Pain Clinical Trials

Efficacy of Liposomal Bupivacaine for Pain Control After Percutaneous Nephrostolithotomy

Start date: August 8, 2017
Phase: Phase 3
Study type: Interventional

Percutaneous nephrostolithotomy (PCNL) is a common endoscopic procedure performed for upper urinary tract calculus disease. Despite being minimally invasive, it is associated with significant postoperative pain, often necessitating inpatient hospitalization and narcotic pain medications. Additionally, one of a number of catheters is often left protruding from the access tract for a period of time following the procedure, adding to patient discomfort. Attempts have been made to study peri-tubular or access tract analgesic installation, which have shown promise.1-2 However, no studies, to our knowledge, have examined the use of liposomal bupivacaine preparations in this regard. In this study we hope to prospectively analyze the use of liposomal bupivacaine injected to the access tract site at the time of PCNL and determine its effects on postoperative narcotic requirement and pain scores. Patients presenting for PCNL will be randomized to either the liposomal bupivacaine or usual care, which involves no injection of local anesthesia. Patients will then be followed during their inpatient stay. Total narcotic requirement (in milligrams) and pain scores (using Wong-Baker FACES rating scale) will be compared.3 Typical postoperative care and discharge criteria will not change during the course of this study.

NCT ID: NCT02945696 Withdrawn - Postoperative Pain Clinical Trials

Abdominal Wall Nerve Blockade: A Comparison With Local Port Site Injection as Well as Between the Use of Ultrasound and Laparoscopy to Guide Placement

Start date: October 2016
Phase: N/A
Study type: Interventional

The investigators will perform a prospective randomized study to compare the effectiveness of laparoscopic-guided abdominal wall nerve blocks with local wound site infiltration and with ultrasounded guided abdominal wall blocks.

NCT ID: NCT02927405 Withdrawn - Postoperative Pain Clinical Trials

Combination of Preoperative Gabapentin and TAP Blocks in Decreasing Postoperative Pain

Start date: March 4, 2020
Phase: Phase 4
Study type: Interventional

There is an increasing trend on decreasing narcotic use and maximizing efficiency in the perioperative care. There are no studies that have compared a TAP block versus a TAP block plus gabapentin for laparoscopic procures.This study will investigate if taking gabapentin and receiving a TAP block decrease post-operative morphine consumption. It will be a randomized controlled, double blind study, with 130 patients between 18-60 years; that will undergo laparoscopic GYN procedures. Secondary outcomes will look at the incidence of nausea, vomiting, and VAS (verbal analog scale) scores. This combination may be helpful because gabapentin will be used to decrease visceral and central pain, and TAP block will decrease somatic pain. Performing a multimodal approach may decrease narcotic consumption, adverse effects and improve pain management.

NCT ID: NCT02506855 Withdrawn - Postoperative Pain Clinical Trials

Intraoperative Transversus Abdominis Plane Block for Gynecologic Surgery (GYNTAP)

GYNTAP
Start date: June 2015
Phase: Phase 3
Study type: Interventional

This study attempts to learn about the effectiveness of a modification to the Transversus Abdominis Plane (TAP) block that works by anaesthetizing the sensory afferents of the abdominal wall postoperatively using ultrasound guidance. The investigators want to see if regional blocks placed by the surgeon intraoperatively to assure regional anesthetic spread in the appropriate plane could reduce error and improve postoperative recovery.

NCT ID: NCT02389907 Withdrawn - Postoperative Pain Clinical Trials

Association Between Patients' Perceptions of Success in Post-op Pain Management and Overall Experience With Care

Start date: June 2015
Phase:
Study type: Observational [Patient Registry]

Assessing the association between patients' perceptions of success with post-operative pain management and overall experience with care.

NCT ID: NCT02209233 Withdrawn - Anxiety Clinical Trials

Effects of Massage on Post-operative Pain in Urologic Patients

Start date: February 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effect that receiving massage therapy post-operatively has on reducing perceived anxiety and pain in urology patients. Secondarily, the result of massage on patient satisfaction, length of hospital stay, and narcotic use will also be studied.

NCT ID: NCT01943240 Withdrawn - Breast Cancer Clinical Trials

Pectoral Nerve Blockade in Mastectomy

Start date: March 2014
Phase: Phase 4
Study type: Interventional

Our routine practice for patients undergoing mastectomy is to include paravertebral peripheral nerve blockade for postoperative analgesia. This study investigates whether the addition of another nerve block targeting the pectoral nerves will improve that analgesia.