IV Acetaminophen for Postoperative Analgesia

Status Terminated

Clinical Trial Summary

The purpose of this study is to evaluate the use of IV acetaminophen for postoperative pain management after laparoscopic cholecystectomy to determine if its use to supplement standard of care pain management decreases the incidence of post-operative nausea and vomiting.

Clinical Trial Description

The recent clinical development of an intravenous (IV) acetaminophen formulation for use in the US has important implications for the management of postoperative pain given its safety profile and suitability for use in the early phase of the postoperative period. In clinical studies a significant opioid-sparing effect has been documented with a substantial percentage of patients avoiding the need for opioid rescue medication altogether. This avoidance or delay in the use of opioids has been shown to reduce undesirable side effects. It is proposed that the use of IV acetaminophen in the post anesthesia care unit (PACU) for postoperative analgesia after laparoscopic cholecystectomy will result in decreased incidence of post operative nausea and vomiting (PONV) and decreased use of narcotics. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01798316
Study type	Interventional
Source	Northwell Health
Contact
Status	Terminated
Phase	Phase 4
Start date	March 2013
Completion date	September 2015

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04633850` - Implementation of Adjuvants in Intercostal Nerve Blockades for Thoracoscopic Surgery in Pulmonary Cancer Patients
Recruiting	`NCT03181620` - Sedation Administration Timing: Intermittent Dosing Reduces Time to Extubation	N/A
Completed	`NCT04579354` - Virtual Reality (VR) Tour to Reduce Preoperative Anxiety Before Anaesthesia	N/A
Recruiting	`NCT06007378` - Optimizing Postoperative Pain Control After Laparoscopic Colorectal Surgery	N/A
Recruiting	`NCT05943015` - Analgesic Efficacy of Quadratus Lumborum, Paravertebral Blocks	N/A
Completed	`NCT04544228` - Ketamine or Neostigmine for Serratus Anterior Plane Block in Modified Radical Mastectomy	N/A
Completed	`NCT03678168` - A Comparison Between Conventional Throat Packs and Pharyngeal Placement of Tampons in Rhinology Surgeries	N/A
Completed	`NCT03286543` - Electrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty Using the SPRINT Beta System	N/A
Completed	`NCT03663478` - Continuous TQL Block for Elective Cesarean Section	Phase 4
Completed	`NCT04176822` - Designing Animated Movie for Preoperative Period	N/A
Completed	`NCT05170477` - Influence of Apical Patency Concept Upon Postoperative Pain After Root Canal Treatment	N/A
Not yet recruiting	`NCT04561856` - Fascia Iliaca Block Supplemented With Perineural Vs Intravenous Dexamethasone	Phase 4
Completed	`NCT06425601` - A Comparison of Silicone Versus Polyvinylchloride (PVC) Drains Following VATS Lobectomy	N/A
Completed	`NCT03612947` - TAP Block in Laparoscopic Cholecystectomy.	Phase 2
Completed	`NCT05974501` - Pre vs Post Block in Total Knee Arthroplasty (TKA)	Phase 4
Completed	`NCT05995912` - Efficacy and Safety of Etoricoxib-tramadol Tablet in Acute Postoperative Pain	Phase 2
Completed	`NCT04571515` - Dose-Response Study of MR-107A-01 in The Treatment of Post-Surgical Dental Pain	Phase 2
Active, not recruiting	`NCT04190355` - The Effect of Irrigant Types Used During Endodontic Treatment on Postoperative Pain	N/A
Recruiting	`NCT05145153` - Incidence of Chronic Pain After Thoracic Surgery
Recruiting	`NCT03697278` - Monitoring Postoperative Patient-controlled Analgesia (PCA)	N/A