Other Clinical Trial - Preemptive Versus Preventive Antiemetic Treatment

Status Not yet recruiting

Clinical Trial Summary

Patients aged between 20 and 70 years, ASA physical status I-III, and scheduled for laparoscopic cholecystectomy under general anaesthesia will be enrolled in the study.

Patients will be randomized to the preemptive group to receive an antiemetic regime 1h before the start of surgery or to the intraoperative group to receive the same antiemetic drugs in the same doses intraoperatively, 30 min before the end of surgery.

In the operating room standard monitoring and a standardized anesthetic technique will be implemented in all patients. Nausea, vomiting, retching and PONV (cumulative) will be recorded at PACU, at 4h, 8h and 24h postoperatively. Pain scores assessed by NRS (numerical rating scale) will be recorded at the same time points. Also, when patients received fluids and solid food by mouth will be recorded.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Postoperative Nausea and Vomiting
Vomiting

Clinical Trial Details

NCT number	NCT03023306
Study type	Interventional
Source	University of Athens
Contact	Argyro Fassoulaki, MD PhD DEAA
Phone	306936701333
Email	afassou1@otenet.gr
Status	Not yet recruiting
Phase	N/A
Start date	November 2018
Completion date	November 2020

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04466046` - The Effect on Anxiolytics With Type of Antiemetic Agents on Postoperative Nausea and Vomiting in High Risk Patients
Completed	`NCT03139383` - Dextrose Containing Fluid and the Postoperative Nausea and Vomiting in the Gynecologic Laparoscopic Surgery	N/A
Recruiting	`NCT04069806` - Preoperative Oral Carbohydrate for Nausea and Vomiting Prevention During Cesarian Section	N/A
Completed	`NCT04043247` - Transcutaneous Electrical Acupoint Stimulation for Prevention of Postoperative Nausea and Vomiting	N/A
Terminated	`NCT01975727` - Dexamethasone for the Treatment of Established Postoperative Nausea and Vomiting	Phase 2
Completed	`NCT03662672` - Rib Raising for Post-operative Ileus	N/A
Completed	`NCT00090155` - 2 Doses of an Approved Drug Being Studied for a New Indication for the Prevention of Postoperative Nausea and Vomiting (0869-090)(COMPLETED)	Phase 3
Recruiting	`NCT05375721` - Prevention of PONV With Traditional Chinese Medicine	N/A
Completed	`NCT02480088` - Comparison of Palonosetron and Ramosetron for Preventing Patient-controlled Analgesia Related Nausea and Vomiting Following Spine Surgery; Association With ABCB1 Polymorphism	Phase 4
Recruiting	`NCT06137027` - Cannabidiol Oil Extract for Prevention of Postoperative Nausea and Vomiting	Early Phase 1
Not yet recruiting	`NCT05529004` - A 6 Months Double Blind Trial to Prevent PONV in Laparoscopic Cholecystectomy	Phase 2
Completed	`NCT02944942` - Risk Factors for Postoperative Nausea/Vomiting	N/A
Recruiting	`NCT02571153` - Low Doses of Ketamine and Postoperative Quality of Recovery	Phase 4
Completed	`NCT02449291` - Study of APD421 as PONV Treatment (no Prior Prophylaxis)	Phase 3
Completed	`NCT02550795` - Dexmedetomidine or Dexmedetomidine Combined With Dexamethasone on Postoperative Nausea and Vomiting in Breast Cancer	N/A
Recruiting	`NCT01442012` - Utility of Acupuncture in the Treatment of Postoperative Nausea and Vomiting in Ambulatory Surgery	N/A
Completed	`NCT01478165` - Comparison of TIVA (Total Intravenous Anesthesia) and TIVA Plus Palonosetron in Preventing Postoperative Nausea and Vomiting	N/A
Unknown status	`NCT01268748` - Single Port Versus Four Ports Laparoscopic Cholecystectomy and Early Postoperative Pain	N/A
Completed	`NCT02143531` - Intravenous Haloperidol Versus Ondansetron for Treatment of Established Post-operative Nausea and Vomiting	Phase 4
Completed	`NCT00734929` - Aprepitant With Dexamethasone Versus Ondansetron With Dexamethasone for PONV Prophylaxis in Patients Having Craniotomy	Phase 4