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Postoperative Infection clinical trials

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NCT ID: NCT06265493 Completed - Geriatrics Clinical Trials

Postoperative Infectious Complications Calculator for Elderly Patients

Start date: June 1, 2021
Phase:
Study type: Observational

The investigators established a first-ever convenient scoring system for clinicians to assess the risk of Postoperative infectious complications (PICs) for elderly patients. Our scoring system can aid in the early detection of potential risks for postoperative infections. Higher-score patients were more likely to experience postoperative infections.

NCT ID: NCT06177444 Active, not recruiting - Clinical trials for Postoperative Infection

Post-operative Antibiotics; Effects on Risk of Infection After Cochlear Implant Surgery

Start date: September 1, 2023
Phase:
Study type: Observational

Currently there is little consensus regarding postoperative antibiotic prophylactic treatment and its effect on the postoperative infection rate after Cochlear implantation. The literature on this subject is contradictory, and very limited. The aim is to assess the impact of postoperative antibiotic treatment on post-operative infection rate, and thereby discuss if postoperative antibiotic treatment has any benefits in the preventing treatment against infectious complication.

NCT ID: NCT06044428 Recruiting - Pneumonia Clinical Trials

Steadysense -Early Detection of Postoperative Infections Through Continuous Temperature Measurement

Start date: August 14, 2023
Phase:
Study type: Observational

The goal of this observational study is to review whether postoperative infections can be detected earlier by a continuous measurement of body temperature of patients compared to single daily measurements. Within 25 weeks 100 patients, which underwent visceral surgery less than 48h ago, will be included. A patch (Steadytemp ®) will be attached to participants, continuously measuring the body temperature. In addition infection parameters and medication of the participants will be documented.

NCT ID: NCT05961930 Recruiting - Clinical trials for Postoperative Infection

Surgeon's Performance in Predicting Postoperative Infections

SPIRIT
Start date: February 1, 2023
Phase:
Study type: Observational

Post-surgical (bacterial) infections are the most frequent post-surgical complications, including deep or superficial wound infections, urinary tract infections, pneumonia, and even sepsis. Approximately 6.5-25% of all surgical patients will develop any type of bacterial infection. To personalize surgical infection management, (Artificial Intelligence) models are in the making to predict which patients are at high or low risk of developing a post-surgical infection. In order to benchmark these prediction models to the predictive capabilities of surgeons, the investigators aim to investigate the performance of surgeons in predicting the risk of a patient developing (any type) of post-surgical infection within 30 days.

NCT ID: NCT05236751 Completed - Hyperglycemia Clinical Trials

Hyperglycemia in Neurosurgery

Start date: May 24, 2021
Phase:
Study type: Observational

Poor glycemic control is recognized as a risk factor for postoperative infection. For the neurosurgical patient, postoperative infection can lead to devastating complications such as meningitis, encephalitis and death. Neurosurgical patients often receive high doses of medications that increase blood glucose levels such as steroids, placing them at a potentially higher risk for postoperative infection. The purpose of this multisite observational study is to assess the impact of severe intraoperative hyperglycemia as a risk factor for postoperative infection in the neurosurgical patient.

NCT ID: NCT05187871 Active, not recruiting - Abdominal Surgery Clinical Trials

Study for Rapid Diagnosis of Postoperative Abdominal Infection

Start date: August 10, 2021
Phase:
Study type: Observational

This is a prospective and exploratory study, which utilizes non-targeted metagenomic next-generation sequencing (mNGS) detecting drain fluid from patients who are suspected of postoperative abdominal infection. This study aims to explore the clinical value of mNGS in the rapid diagnosis of postoperative abdominal infection, to refine the pathogenic bacteria spectrum, and to establish a novel procedure for postoperative abdominal infection diagnosis.

NCT ID: NCT05052619 Recruiting - Antibiotics Clinical Trials

Preventive Therapy of Postoperative Intra-abdominal Infection Based on Serum Lactate Changes

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

Intra-abdominal infection is one of the most serious complications after pancreatic resection. The preventive use of antibiotics intraoperatively could reduce the incidence rate of postoperative intra-abdominal infection. According to the previous retrospective study, changes of serum lactate level on postoperative day1 could predict the incidence rate of postoperative intra-abdominal infection. This prospective RCT is to further validate and promote the findings and conclusion.

NCT ID: NCT05021315 Recruiting - Clinical trials for Cesarean Section Complications

Vaginal Cleaning Using Povidone Iodine Before CS to Reduce Postoperative Wound Infection

Start date: September 15, 2021
Phase: Phase 3
Study type: Interventional

The aim of work to assess the effectiveness of preoperative vaginal cleansing with povidone iodine on reduction of post caesarean section wound infection Research questions: Does vaginal cleaning using povidone iodine before cesarean section has effect on reduction of postoperative wound infection??

NCT ID: NCT04994275 Active, not recruiting - Clinical trials for Postoperative Complications

Impact of Iron Deficiency on the Incidence of Postoperative Infections

CARIPO
Start date: November 3, 2021
Phase:
Study type: Observational

Iron deficiency is a common state during the perioperative period. Data from literature do not allow us to conclude on how perioperative iron deficiency influences postoperative infections occurrence. This prospective observational study aims to assessed the postoperative infections incidence according to the preoperative iron-stock status.

NCT ID: NCT04636242 Enrolling by invitation - Shoulder Surgery Clinical Trials

Photodynamic Therapy for Cutibacterium Acnes (C. Acnes) Decolonization of the Shoulder Dermis

Start date: August 22, 2019
Phase: Phase 3
Study type: Interventional

This is a prospective, randomized controlled trial to evaluation the ability of 5-aminolevulinic acid HCL topical solution photodynamic therapy to decrease the colonization of Cutibacterium acnes (C. acnes- a bacteria commonly found in the dermis of the skin surrounding the shoulder) in order to decrease postoperative joint infections. -Aminolevulinic acid (ALA) is a naturally occurring metabolite in the synthesis of pathway of cellular heme production. Adding ALA to bacteria encourages porphyrin production which serve as the immediate precursors to heme production. When these porphyrins are illuminated with blue light at an emission peak of 407-420nm, these metabolites become exothermic and cause internal destruction of the bacterial cells. This therapy does not cause any damage to the mammalian cells, which makes PDT safe for human skin treatment.