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Postictal Delirium clinical trials

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NCT ID: NCT04028596 Completed - Depression Clinical Trials

Measuring Blood Flow in the Brain After Epileptic Activity

SYNAPSE
Start date: December 5, 2019
Phase: Phase 2
Study type: Interventional

In this clinical trial, postictal phenomena (i.e., headache, delirium) will be investigated after administration of acetaminophen and nimodipine in depressed patients receiving electroconvulsive therapy (ECT). Postictal phenomena are thought to result from decreased cerebral blood flow and decreased oxygen concentration in the brain. It is expected that acetaminophen and nimodipine will reduce these postictal phenomena, compared to no treatment, because they target these mechanisms.