A Pilot Study of SPG Block for PTSD

Status Completed

Clinical Trial Summary

Some patients with Post Traumatic Stress Disorder (PTSD) respond only partially to medication. This study is a pilot study investigating whether blocking the SPG helps reduce the symptoms of PTSD. This study does not involve treatment with medications. It is a proof of principal study.

Clinical Trial Description

The sphenopalatine ganglion (SPG) is a collection of neurons involved in autonomic regulation (which refers to bodily processes that are automatic like heart rate and blood pressure). Blocking the SPG is used to treat disorders, such as migraines or cluster headaches (short, severe headaches that occur together). The procedure will be performed by a doctor who specializes in ear, nose throat surgery. The block consists of the injection of a numbing agent (similar to the type used by dentists) to the SPG. After the SPG block, we will follow patients for 8 weeks to see how they feel. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05743543
Study type	Interventional
Source	New York State Psychiatric Institute
Contact
Status	Completed
Phase	Early Phase 1
Start date	May 28, 2019
Completion date	June 1, 2023

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