Effect of TMS on PTSD Biomarkers

Status Recruiting

Clinical Trial Summary

The study will (1) assess feasibility of a TMS treatment in an underserved population; (2) determine if this TMS treatment protocol improves PTSD symptoms and biological markers of PTSD such as brain functioning and startle responses; (3) define new brain targets for future TMS studies; (4) provide the first data for individual differences, which will help personalize treatment for PTSD patients; (5) improve knowledge of the neurobiology of PTSD and treatment response.

Clinical Trial Description

Posttraumatic stress disorder is a psychiatric disorder that can develop in response to a traumatic event, and half of civilians living in inner-city areas with high levels of violence suffer from PTSD. The currently recommended treatment for PTSD is focused on discussing the trauma, but a third to half of patients cannot participate or do not benefit from this treatment, especially individuals with low levels of education or literacy. Therefore, new treatments for PTSD are needed. The study will (1) assess feasibility of a TMS treatment in an underserved population; (2) determine if this TMS treatment protocol improves PTSD symptoms and biological markers of PTSD such as brain functioning and startle responses; (3) define new brain targets for future TMS studies; (4) provide the first data for individual differences, which will help personalize treatment for PTSD patients; (5) improve knowledge of the neurobiology of PTSD and treatment response. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04563078
Study type	Interventional
Source	Emory University
Contact	Sanne van Rooij, PhD
Phone	404-251-8926
Email	sanne.van.rooij@emory.edu
Status	Recruiting
Phase	N/A
Start date	February 15, 2021
Completion date	July 1, 2026

View Details

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