Anger and Psychotrauma: Data From Military and Civilians

Post-traumatic Stress Disorder Clinical Trial

— COPMiCiv  

Official title:

Anger and Psychotrauma: Data From Military and Civilians

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04518267
• Other study ID #: 2019PPRC16
• Secondary ID: 2020-A00507-32
• Status: Recruiting
• Start date: September 21, 2020
• Est. completion date: September 2024

Study information

• Verified date: April 2023
• Source: Direction Centrale du Service de Santé des Armées
• Contact: Anaïs MARMUSE
• Phone: 328382250
• Email: anais.marmuse[@]intradef.gouv.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Post-Traumatic Stress Disorder (PTSD) is mainly associated with several emotions such as anger, guilt or shame. By interfering with psychotherapeutic work these emotions can be problematic. When suffering from PTSD, pervasive anger can also have relational consequences. Anger and PTSD are mutually reinforcing: anger can aggravate PTSD symptoms and aggressive behaviours, and conversely, PTSD promotes high levels of anger and aggression. A few explanatory hypotheses have been proposed. In terms of personality factors, anger-treatment may promote the severity of PTSD symptoms and the development of aggressive behaviours. In terms of stressors, exposure to combat and combat-related moral harms could play a role in the relationship between PTSD, anger and traumatic experiences over the course of life. Finally, in clinical terms, in the presence of PTSD, anger and aggressive behaviours may be triggered by substance abuse and depression.

Within the Anglo-Saxon literature, it is recognized that both civilians and military personnel with PTSD exhibit high levels of anger, with a possible predominance among military personnel. While we know that anger management mechanisms can be strongly influenced by cultural aspects and the type of event, there is no data in the French population.

This study proposes to fill in our knowledge of anger-PSTD relationships in the French population and by comparing civilian and military population.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 50
• Est. completion date: September 2024
• Est. primary completion date: September 2024
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• To have a PTSD diagnosis

• To be at least 18 years of age

Exclusion Criteria:

• To suffer from trauma-related physical condition (including Traumatic Brain Injury)

Related Conditions & MeSH terms

• Post-traumatic Stress Disorder
• Stress Disorders, Post-Traumatic
• Stress Disorders, Traumatic

Intervention

Behavioral:
• Structured clinical interview
A structured clinical interview will be performed at enrollment.
• Psychological questionnaires
Several psychological questionnaires will be performed at enrollment.

Locations

Country	Name	City	State
France	Centre hospitalier d'Arras	Arras
France	3ème Centre médical des Armées	Lille
France	Centre régional psychotrauma Hauts-de-France	Lille
France	Centre Hospitalier de Cadillac	Lormont
France	CHU de Nice	Nice
France	CHU-Lenval hôpitaux	Nice
France	Centre Hospitalier Léon-Jean Grégory de Thuir	Thuir
France	Groupe Hospitalier Paul Guiraud	Villejuif

Sponsors (1)

Lead Sponsor	Collaborator
Direction Centrale du Service de Santé des Armées

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Anxiety score	Spielberger's State-Trait Anger Expression Inventory-II (STAXI-II) will be used to assess anxiety	At enrollment
Primary	PTSD severity score	Clinician-Administered Posttraumatic Stress Disorder Scale (CAPS-5) will be used to assess PTSD severity score. CAPS-5 score may range from 0 to 120 with higher scores meaning greater PTSD severity.	At enrollment
Primary	Number of life traumatic events	Life Event Checklist (LEC) will be used to assess the number of traumatic events experienced by participants throughout their lifetime	At enrollment
Secondary	Aggressivity score	Aggressivity Questionnaire (AQ12) will be used to assess aggressivity score. AQ12 score may range from 6 to 72 with higher scores meaning higher aggressivity levels.	At enrollment
Secondary	Anger Rumination score	Anger Rumination Scale (ARS) will be used to assess anger rumination score. ARS score may range from 19 to 76 with higher scores corresponding to greater levels of anger rumination.	At enrollment
Secondary	Alcohol consumption score	Alcohol Use Identification Test (A.U.D.I.T.) will be used to assess alcohol consumption score Score = 5: at risk use; Score = 8 (7 in women): harmful use; Score = 12 (11 in women): likely alcohol dependence	At enrollment