A mGlu2/3 Agonist in the Treatment of PTSD

Status Terminated

Clinical Trial Summary

In this study, we propose to employ a randomized, double-blind, placebo-controlled, outpatient clinical trial to test the efficacy, safety, and tolerability of a 160 mg and 40 mg challenge of the mGlu2/3 agonist pomaglumetad methionil relative to placebo in modulating fear-potentiated startle response and behavior in adults with post-traumatic stress disorder (PTSD) (N=30). Each participant will receive a single dose of the study drug (40 mg vs 160 mg vs placebo in a 1:1:1 ratio).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02234687
Study type	Interventional
Source	New York University School of Medicine
Contact
Status	Terminated
Phase	Phase 1
Start date	September 2014
Completion date	September 11, 2016

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