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Carvedilol Versus Placebo for Treatment in Post Traumatic Stress Disorder (PTSD)

Post-Traumatic Stress Disorder Clinical Trial

Official title:
A Randomized, Double-Blind, Placebo-Controlled, Flexible-Dose Study to Assess the Safety and Efficacy of Carvedilol Versus Placebo in the Treatment of Post Traumatic Stress Disorder

Clinical Trial Summary

The investigators hypothesize that carvedilol, at less then therapeutic doses for cardiac effect, will reduce symptoms of Post Traumatic Stress Disorder.

Clinical Trial Description

This initial proof of concept trial design is intended to explore multiple variables. Fist, it is intended to determine if carvedilol has any statistically significant effect over placebo on the various overall symptoms, symptom clusters, or individual symptoms of post traumatic stress disorder. Next, the flexible dosing trial design is aimed to detect the therapeutic dose, or dosing range for carvedilol when used in the treatment of PTSD ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01221792
Study type Interventional
Source Columbia Northwest Pharmaceuticals
Contact
Status Unknown status
Phase Phase 2
Start date October 2010
Completion date August 2011
View Details
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