Carbetocin Versus Syntometrine in Obese Women Undergoing Elective Cesarean

Status Completed

Clinical Trial Summary

to compare effectiveness and tolerability of carbetocin versus syntometrine in prevention of Postpartum hemorrhage after cesarean section

Clinical Trial Description

A double-blind randomized study conducted on 1200 obese pregnant subjected randomly either to single 100 μg IV dose of carbetocin (600 women) or combination of 5 IU oxytocin and 0.5 mg ergometrine (600 women) after fetal extraction and before placental removal.

Prevention of postpartum haemorrhage (PPH) after cesarean section (CS) had been evaluated by measurement of drop of Hemoglobin and hematocrit, incidence of PPH and number of subjects needed additional oxytocic ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03693599
Study type	Interventional
Source	Cairo University
Contact
Status	Completed
Phase	Phase 4
Start date	October 1, 2018
Completion date	September 30, 2019

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03680339` - The Effect of Preoperative and Post Operative Misoprostol Administration on Intraoperative Blood Loss and Postpartum Hemorrhage in CS	Phase 4
Completed	`NCT03707132` - Tourniquet Reduces Blood Loss in Postpartum Hemorrhage During Hysterectomy for Placenta Accreta
Recruiting	`NCT02306733` - Ergometrine Versus Oxytocin in the Management of Atonic Post-partum Haemorrhage (PPH) in Women Delivered Vaginally	Phase 3
Completed	`NCT01866241` - Combating Maternal Mortality in Uganda: An Assessment of the Role of Misoprostol in Prevention of Post-Partum Hemorrhage	Phase 3
Not yet recruiting	`NCT01236482` - Oxytocin in Cesarean Delivery	Phase 4
Completed	`NCT03784794` - Patient Blood Management for Massive Obstetric Hemorrhage	N/A
Enrolling by invitation	`NCT06255496` - QStat Cartridge in Obstetric Patients
Recruiting	`NCT04401839` - Amr Maneuver for Prevention of Postpartum Hemorrhage	N/A
Recruiting	`NCT06219538` - DAISY Uterine Drain Device Evaluation	N/A
Not yet recruiting	`NCT06333340` - Comparative Efficacy of Carbetocin and Oxytocin in Parturients at Risk of Atonic Postpartum Hemorrhage Undergoing Elective Cesarean Delivery	N/A
Completed	`NCT01863706` - Misoprostol Versus Oxytocin for Prevention of Post Partum Hemorrhage	Phase 1
Terminated	`NCT04277962` - Estimating Blood Loss Using TritonTM in Vaginal Deliveries: A Validation Trial	N/A
Completed	`NCT04723979` - NovoSeven® in Severe Postpartum Haemorrhage - Experiences From UK, DK, FR, NL
Completed	`NCT03570723` - Glove-loaded Foley's Catheter Tamponade for Cesarean Section for Placenta Previa	N/A
Completed	`NCT03117647` - Mansoura-VV Uterine Compression Suture for Primary Atonic Postpartum Hemorrhage	N/A
Active, not recruiting	`NCT03069859` - Use of TXA to Prevent Postpartum Hemorrhage	Phase 2
Not yet recruiting	`NCT03891082` - A Comparative Study Between Bakri Balloon and B Lynch Suture Used to Control Primary Postpartum Hemorrhage After Cesarean Section	N/A
Not yet recruiting	`NCT03463070` - Misoprostol Before and After Cesarean Section	Phase 3
Recruiting	`NCT05532215` - Sublingual Misoprostol in Reduction of Caesarean Blood Loss	N/A
Completed	`NCT03907605` - Anti-Mullerian Hormone (AMH) is a Marker for Ovarian Reserve. There Are Many Studies About AMH Changes in Ovarian Surgery, But Little is Known for Other Surgeries. We Seek to Investigate the Hormone Variations Before and After Uterine Artey Ligation for Postpartum Hemorrage (PPH)