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Post-operative Pain clinical trials

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NCT ID: NCT04182828 Recruiting - Post-operative Pain Clinical Trials

Effect of Intravenous Lidocaine on Immediate Post-operative Pain, Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy: A Randomized Placebo Controlled Trial

Start date: November 25, 2019
Phase: Phase 4
Study type: Interventional

Lidocaine is a drug that has multiple uses. One of these is that when intravenously administered it is effective in reducing post-operative pain. The aim of this study is to investigate the beneficial effects of intravenous lignocaine on reducing pain, nausea and vomiting after laparoscopic cholecystectomy. Also, by this research, we are aiming to find a suitable alternative analgesic.

NCT ID: NCT04109573 Recruiting - Post Operative Pain Clinical Trials

Function Following Laser for Anal Intraepithelial Neoplasia (FLAN)

FLAN
Start date: March 1, 2018
Phase: N/A
Study type: Interventional

High-grade squamous intraepithelial lesions (HSIL) and anal cancer are rising in incidence and at highest risk are HIV positive men who have sex with men (MSM). This pilot study assessing anal function and patient-reported outcomes before and after laser ablation of HSIL will add to the evidence that such a therapy is an acceptable and safe treatment to offer in a preventative setting.We will be recruting HIV positive and negative MSM.

NCT ID: NCT04046068 Recruiting - Post-operative Pain Clinical Trials

Multimodal Perioperative Pain Management: ComfortSafe Program

Start date: May 11, 2020
Phase:
Study type: Observational

Proposed is a demonstration project to characterize the immediate, short-term and long-term pain and other post-operative outcomes of 60, self-selected breast (n=20), caesarian-section (n=20) and abdominal (n=20) surgical patients who receive opioid-sparing, multimodal anesthesia and pain management care as guided by the ComfortSafe Pyramid.

NCT ID: NCT04005326 Recruiting - Post Operative Pain Clinical Trials

Quadratus Lumborum Block Versus Fascia Iliaca Block for Hip Arthroplasty

Start date: July 5, 2019
Phase: N/A
Study type: Interventional

Quadratus lumborum block is a newly developed block with good performance in lower abdominal surgery. In a cadaveric study, the spread of local anesthetic in the anterior approach of QL block (QL3) was reported to cover nerve roots from T10 to L3. Thus, it was hypothesized that this approach could be used in hip surgeries with minimal motor affection. This study aims to compare QL3 block and suprainguinal Fascia Iliaca block in the duration of postoperative analgesia, pain scores, motor power in quadriceps muscle, and side effects.

NCT ID: NCT03304444 Recruiting - Post Operative Pain Clinical Trials

A Comparison of Exparel to Bupivacaine in TAP Block for Abdominal Gynecologic Surgery

Start date: August 2016
Phase: Phase 3
Study type: Interventional

This study evaluates the comparison between liposomal bupivacaine versus bupivacaine HCl in Transversus Abdominis Plane blocks for gynecologic surgery on the length of stay in the hospital, total narcotic use, and overall complications rates.

NCT ID: NCT03277391 Recruiting - Thoracic Surgery Clinical Trials

Serratus Anterior Plane Block: Post-operative Analgesia in Video-assisted Thoracic Surgery

Serrathos
Start date: April 14, 2017
Phase: N/A
Study type: Interventional

The objective of the study is to compare the efficacy of the Serratus Anterior Plane block (SPB) realised in its deep plane, with a multi-holed catheter in place for twenty four hours, to a standard intravenous analgesia for small videoassisted thoracic surgery interventions. The objective is also to evaluate the resorption rate of local anesthetic at this level, and make a population pharmacokinetic analysis.

NCT ID: NCT03056521 Recruiting - Post Operative Pain Clinical Trials

Effect of Preoperative Information About Pain on Postoperative Pain Experience and Patient Satisfaction

epps
Start date: June 2016
Phase: N/A
Study type: Interventional

Patients are randomized into 2 groups. The intervention group which receives preoperative counseling about pain and a control group which does not receive this counseling. The patients are followed up looking at pain scores and pain experience and satisfaction with pain management for 2 days post operative.

NCT ID: NCT02549105 Recruiting - Post Operative Pain Clinical Trials

Lidocaine-Prilocaine Cream (EMLA) Topical Application Versus Wound Infiltration With Lidocaine After Cesarean Section

Start date: October 2014
Phase: Phase 4
Study type: Interventional

A Comparison Between Lidocaine-Prilocaine Cream (EMLA) Application And wound Infiltration with Lidocaine For Post Caesarean Section Pain Relief : A Randomized Controlled Trial.

NCT ID: NCT02523846 Recruiting - Post-operative Pain Clinical Trials

Patient Re-education vs. Background Morphine to IV-PCA in Patient With Unsatisfactory Analgesia Post Laparotomy

Start date: August 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to improve IV-Patient Controlled Analgesia (IV-PCA) technique for postoperative analgesia. Investigators are comparing between patient re-education and the background morphine infusion among patients who fail to achieve satisfactory analgesia using IV-PCA Morphine after laparotomy.

NCT ID: NCT02483689 Recruiting - Post Operative Pain Clinical Trials

Evaluation of Local Anesthetic at Incision Site

Start date: August 2015
Phase: N/A
Study type: Interventional

Patient will have usual appendectomy surgery with an injection of local or saline at incision site either before or after the incision at random. The clinical hypothesis of this trial is that pediatric patients who undergo a local anesthetic pre-incisional and/or post-incisional will reduce the amount of postoperative pain and therefore reduce the amount of analgesics required to keep the patient satisfied. Primary: To determine if local anesthetic reduces postoperative pain. Secondary: To assess the timing of local anesthetic injection affects postoperative pain.