Post Inflammatory Hyperpigmentation Clinical Trial
Official title:
Tranexamic Acid Versus Fractional CO2 Laser in Post-inflammatory Hyperpigmentation in Acne Patients
comparing between the effect of intradermal injection of TXA and low power low density fractional CO2 lasers on post acne hyperpigmentation
Randomized controlled split-face study. One side of the face will be assigned to TXA intradermal microinjection using Kapron 500mg/5ml ampoules (Amoun Pharmaceutical Company), the dose of 1 ml syringe with 100mg/ml. TXA will be prepared under sterile conditions. Injections will be applied intradermally on hyperpigmented areas at 1cm intervals. The injection will be repeated every two weeks for three months. The other side of the face will be randomly assigned to low power fractional CO2 laser with a power of 12 watts, spacing 700 micrometers (low density), and dwell time 300 microsecond every four weeks for three months. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT05327361 -
LiftActiv B3 in Post Inflammatory Hyperpigmentation (PIHP)
|
Phase 2 | |
| Not yet recruiting |
NCT03850119 -
Nanofat on Wound Healing and Scar Formation
|
N/A | |
| Not yet recruiting |
NCT05883657 -
Tolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-Inflammatory Hyperpigmentation)
|
N/A | |
| Completed |
NCT03402893 -
The Use of Onexton in Moderate Acne Vulgaris for Patients With Skin of Color
|
Phase 4 | |
| Completed |
NCT04704245 -
Effectiveness of Epidermal Growth Factor-containing Ointment on the Solar Lentigines
|
N/A | |
| Completed |
NCT02492373 -
Topical Corticosteroids on the Incidence of Postinflammatory Hyperpigmentation After QsNdYAG Laser
|
N/A | |
| Completed |
NCT05704114 -
Tazarotene 0.045% Lotion for Treating PIE and PIH in Subjects With Acne
|
Phase 4 | |
| Completed |
NCT01038869 -
Efficacy and Safety Study of Finacea to Treat Acne Vulgaris and Post-Inflammatory Hyperpigmentation (PIH)
|
Phase 4 | |
| Not yet recruiting |
NCT06361251 -
Interventional, Monocentric, Double-blind Randomized Category 2b Study Evaluating the Evaluation of the Tolerance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post -Inflammatory Hyperpigmentation (Pih)) on the Face
|
N/A | |
| Not yet recruiting |
NCT06305897 -
Evaluation of the Tolerance (Main Objective) and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-inflammatory Hyperpigmentation) on the Face
|
N/A |