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Clinical Trial Summary

Posner-Schlossman syndrome, or glaucomatocyclitic crisis, is a condition characterized by recurrent, acute attacks of mild, nongranulomatous, anterior uveitis accompanied by markedly elevated intraocular pressure. Most of patients are the 20 to 50-year-old young adults, with unilateral eye involvement. PSS was originally deemed benign, but is now recognized as a relatively rare cause of chronic secondary glaucoma,especially in patients with recurrent episodes. This relatively rare disease is likely the result of the infections of a variety of organisms, and the bulk of literature supports the cytomegalovirus (CMV) as the leading cause.

This study is an observational study that does not interfere with the normal clinical diagnosis and treatment process. The investigators in this study focus on observing the clinical symptoms and outcome of PSS, analyzing the factors that affect the prognosis of PSS, studying the association of its pathogenesis with the psychological status and the behavioral types of PSS patients; exploring the relationship between infection (CMV, HSV, Hp) and PSS; and studying the changes of local and systemic cytokine expression and its significance in patients with PSS.


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT03233477
Study type Observational [Patient Registry]
Source Peking University
Contact Shushan Li, MD
Phone 0086-135-5237-4266
Email shushan_li@yeah.net
Status Recruiting
Phase
Start date July 31, 2014
Completion date July 31, 2024

See also
  Status Clinical Trial Phase
Recruiting NCT04590183 - The Effectiveness and Safety of FK-506 for the Treatment of Posner-Schlossman Syndrome N/A