Port-wine Stains (PWS) Clinical Trial
Official title:
The Angioma's Treatment Evaluation With Laser Doppler Imaging (LDI)
Based on the Doppler effect, Laser Doppler Imaging (LDI) uses the interaction of light with
moving erythrocytes to visualize perfusion in the microcirculatory system.
The new device to be used in this study have been adapted specifically for the application,
facilitating its use in clinic. It has been designed to take a standard white light image of
the area under inspection simultaneously with the perfusion image to facilitate clinical
assessment.
Port-wine stain (PWS) birthmarks are congenital, low-flow vascular malformations of the skin
found in approximately 0.3% of children. They are commonly found on the face and neck and
may cause serious psychological consequences.
Lasers are the modality of choice for the treatment of PWS birthmarks. The use of PDL is
very effective in PWS in closing the blood vessels and diminishing therefore the redness of
the skin. Repeated laser treatment is necessary to achieve the desired clinical outcome.
Actually, the efficacy of the treatment of PWS by the laser is obtained by clinical
inspection and digital photography.
By measuring the activity and intensity of the microcirculation present in and under the
skin, the Laser-Doppler (LDI) will be capable of measuring the effect of Pulsed dye laser
(PDL) treatment for port-wine stains.
n/a
Observational Model: Case-Only, Time Perspective: Prospective