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A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks.

Port Wine Stain Clinical Trial

Official title:
Phase I Combined Use of Pulsed Dye Laser and Rapamycin

Clinical Trial Summary

The purpose of this study is to improve port wine stain therapeutic outcome in response to laser therapy. The researchers want to determine whether the combined use of pulsed dye laser therapy and rapamycin will improve PWS therapeutic outcome.

Clinical Trial Description

The researchers want to combined use of pulsed dye laser to induce port wine stain blood vessel injury, and rapamycin directly inhibits the proliferation of vascular endothelial cells driven by vascular endothelial growth factor which preventing port wine stain angiogenesis and recanalization, to improve port wine stain lesion blanching. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00800722
Study type Interventional
Source University of California, Irvine
Contact
Status Completed
Phase Phase 1
Start date November 2008
Completion date June 2014
View Details
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