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Polyuria clinical trials

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NCT ID: NCT03810027 Completed - Nocturia Clinical Trials

Prevalence and Risk Factors Nocturnal Polyuria in Female OAB

Start date: July 1, 2009
Phase:
Study type: Observational

Nocturnal polyuria may decrease the treatment efficacy of overactive bladder syndrome (OAB); and adjuvant medication, such as desmopressin, may be needed for the treatment of nocturnal polyuria. The knowledge of prevalence and risk factors of nocturnal polyuria might be important for the treatment of OAB. Thus, our aim is to describe the prevalence and risk factors of nocturnal polyuria in women with OAB.

NCT ID: NCT03201419 Completed - Nocturia Clinical Trials

A Trial to Investigate Efficacy, Safety and Tolerability of FE 201836 for Nocturia Due to Nocturnal Polyuria in Adults

Start date: July 27, 2017
Phase: Phase 2
Study type: Interventional

The purpose of this trial was to investigate the efficacy, safety and tolerability of different oral doses of FE 201836, with desmopressin as a benchmark, during 12 weeks of treatment for nocturia due to nocturnal polyuria in adults

NCT ID: NCT03116191 Completed - Clinical trials for Nocturia Due to Nocturnal Polyuria

Trial of SK-1404 for Nocturia Due to Nocturnal Polyuria in Japanese Subjects

Start date: February 23, 2017
Phase: Phase 2
Study type: Interventional

The purpose of this trial is to demonstrate efficacy of SK-1404 against placebo for the treatment of subjects with nocturia due to nocturnal polyuria, during 4 weeks of treatment.

NCT ID: NCT03051009 Completed - Nocturia Clinical Trials

Trial Investigating the Long Term Safety and Tolerability of Desmopressin Orally Disintegrating Tablets (ODT) for Nocturia Due to Nocturnal Polyuria in Japanese Subjects

Start date: January 11, 2017
Phase: Phase 3
Study type: Interventional

Demonstrate the safety and tolerability of desmopressin ODT during long-term treatment of subjects with nocturia due to nocturnal polyuria, for up to 1 year

NCT ID: NCT02981459 Withdrawn - Clinical trials for Bladder Pain Syndrome

Mirabegron for the Treatment of Pain Motivated Urinary Frequency and Urgency in Women

Start date: December 8, 2017
Phase: Phase 4
Study type: Interventional

The specific purpose of this study is to provide objective data in prospective open label design (n=40) to support the use of Mirabegron as a treatment for pain related urinary frequency and urgency. Women with bladder pain have a poor response to traditional anticholinergic therapy for their symptoms of frequency and urgency.

NCT ID: NCT02905682 Completed - Nocturia Clinical Trials

Trial of Desmopressin Orally Disintegrating Tablets (ODT) for Nocturia Due to Nocturnal Polyuria in Japanese Female Subjects

Start date: September 2016
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to demonstrate efficacy of desmopressin ODT against placebo for the treatment of female subjects with nocturia due to nocturnal polyuria, during 12 weeks of treatment.

NCT ID: NCT02904759 Completed - Nocturia Clinical Trials

Trial of Desmopressin Orally Disintegrating Tablets (ODT) for Nocturia Due to Nocturnal Polyuria in Japanese Male Subjects

Start date: September 2016
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to demonstrate efficacy of desmopressin ODT against placebo for the treatment of male subjects with nocturia due to nocturnal polyuria, during 12 weeks of treatment.

NCT ID: NCT02195713 Completed - Oliguria Clinical Trials

Evaluation of a Novel Electronic Urine Output Monitor (eUOM)

Start date: July 2014
Phase: N/A
Study type: Observational

Urine output and urine drain line pressure were monitored while urine was drained into either: 1. Accuryn Urine Output Monitor (Potrero Medical) OR 2. Criticore Monitor (Bard Medical)

NCT ID: NCT01879137 Completed - Healthy Clinical Trials

Copeptin After Arginine Infusion in Polyuria-Polydipsia Syndrome

Start date: June 2013
Phase: N/A
Study type: Observational

the purpose of the study is to investigate whether arginine infusion is a new tool to differentiate patients with diabetes insipidus, primary polydipsia and healthy subjects.

NCT ID: NCT01439997 Completed - Nocturia Clinical Trials

Desmopressin Melt Therapy in Nocturnal Polyuria Patients: Pharmacodynamic Study

Start date: March 26, 2012
Phase: Phase 4
Study type: Interventional

The objective of this study is to find out what the pharmacodynamic (PD) characteristics of desmopressin melt are in nocturia patients (compared to healthy volunteers and children). The main questions the investigators want to answer are: - Are differences related to the pathophysiological factors involved in nocturia? - Are there age/gender/size differences? - Can the investigators identify patients who are likely to develop hyponatraemia? - Can the investigators individualize treatment and reduce risk for hyponatraemia? The patient will be given a prescription to buy Minirin Melt 60µg at the local pharmacy. During 30 days, the patient has to take Minirin Melt 60µg in the evening before going to bed. There are two groups of patients: Group A: Patients that still have to undergo an evaluation phase, according to standard procedures (e.g. osmolality test, blood sample). This procedure is not a part of this study. The study starts when the 1st Minirin Melt tablet has been taken (= day 1). Group B: This group already went through the evaluation phase (by participation to study 1 or study 3 as mentioned above) and they have been prescribed Minirin Melt 60 µg ambulatory. The study starts when the patients takes his first prescribed Minirin Melt tablet: - On day 3 and day 7 a blood sample will be taken at the UZ Ghent for safety control (Na+, K+, creatinin, osmolality = good clinical practice guideline). These first 2 visits (day 3 and day 7) are standard procedure. If the patient is at high risk for side effects, blood has to be taken during the first 7 days. - On day 3 the patient has to give a urine sample. - Patients have to fill out a frequency/volume chart during the first 14 days. - On day 30, a 3rd blood sample will be taken