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Polyps clinical trials

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NCT ID: NCT02522702 Active, not recruiting - Colonic Polyps Clinical Trials

Computer Assisted Optical Assessment of Small Colorectal Polyps

Start date: August 2015
Phase: N/A
Study type: Observational

The aim of the study is to develop a computer program which is able to distinguish between adenomatous and non- adenomatous polyps on the basis of optical features of the polyps. Still images of polyps (< 10 mm of size) will be collected during routine colonoscopy procedures. All polyps will be resected endoscopically so that histopathological diagnoses (gold standard) can be notified. In the validation phase of the study a computer program will be established which aims to distinguish between adenomatous and non- adenomatous polyps on the basis of optical features derived from still images. The program will operated using the the random forest learning method. Afterwards, in the testing phase of the study, still images of 100 polyps (not used in the validation phase) will be presented to the computer program. The establishment of a well- functioning computer program is the primary aim of the study.

NCT ID: NCT02516748 Completed - Colon Polyps Clinical Trials

Real-time Diagnosis of Colorectal Polyps Using Narrow-Band Imaging

Start date: August 2015
Phase: N/A
Study type: Observational

Accurate optical diagnosis of colorectal polyps could allow a "resect and discard" strategy with surveillance intervals determined based on the results of the optical biopsy. The investigators perform education to characterize the histology of diminutive and small colorectal polyps by using narrow band imaging (NBI). After education program, the investigators prospectively evaluate real-time optical biopsy analysis of polyps with NBI by 15 gastroenterologists at a medical check up center.

NCT ID: NCT02492685 Withdrawn - Gallbladder Polyp Clinical Trials

Quantificational Enhancement Pattern Analysis Using a Novel Software "Vuebox" of Contrast-enhanced Harmonic Endoscopic Ultrasonography for Differential Diagnosis Between Adenomas and Cholesterol Polyps

Start date: July 2015
Phase: N/A
Study type: Interventional

The investigators' study is a prospective study to evaluate the enhancement pattern of contrast-enhanced endoscopic ultrasonography and suggest the criterions for differential diagnosis between gallbladder polyps by using software program of quantitative analysis.

NCT ID: NCT02484079 Completed - Clinical trials for Colorectal Neoplasms

Comparative Effectiveness of Hot Versus Cold Snare Polypectomy of Small Colorectal Polyps

HOT/COLD
Start date: May 18, 2015
Phase: N/A
Study type: Interventional

This study aims to investigate the comparative effectiveness between polyp removal with or without electrical current. The investigators want to include 600 polyps in the trial. It is known that polyps have the potential to develop to cancer if left in situ, but the investigators do not know the best way to remove them completely.

NCT ID: NCT02479893 Completed - Colonic Polyps Clinical Trials

Cold Snare,Hot Snare and APC Polypectomy for the Complete Removal of Small Left Sided Colon Polyps

Start date: January 2015
Phase:
Study type: Observational

Given the limited existing data regarding the advantages and limitations of the existing techniques in the removal of colonic polyps the investigators designed a prospective study in order to compare cold snare vs hot snare vs argon plasma coagulation for the compete removal of colonic polyps of the left colon up to a diameter of 0.8cm.

NCT ID: NCT02478918 Completed - Polyps Clinical Trials

Automated Telephone Reminder for Colonoscopy

Start date: June 2015
Phase: N/A
Study type: Interventional

This is a quality improvement study to determine the impact of an automated telephone reminder on the quality of bowel preparation in patients undergoing outpatient colonoscopy.

NCT ID: NCT02476747 Recruiting - Colonic Polyp Clinical Trials

Cold Snare Polypectomy Versus. Endoscopic Mucosal Resection

Start date: June 2015
Phase: N/A
Study type: Interventional

The investigators will investigate the efficacy of EMR compared to CSP in treatment of small colon polp (6~10mm). One aim of this study was to investigate the necessity of EMR on resection of small colon polyp.

NCT ID: NCT02472197 Completed - Endometrial Polyps Clinical Trials

Morcellator Versus Resectoscope in the Treatment of Uterine Polyps by Hysteroscopy

RESMO
Start date: September 2015
Phase: N/A
Study type: Interventional

Intrauterine pathologies are currently treated by hysteroscopic resection. In this surgical procedure, the intrauterine pathology is resected by a transcervical approach in several fragments using a mono or bipolar cove after distension of the uterine cavity and by endoscopic control. The main risks of this surgery are: uterine perforation and OHIA (operative hysteroscopy intravascular absorption) syndrome. Hysteroscopic morcellators are new intrauterine devices, recently appeared on the French market. In comparison to classical resectors, morcellators have several theoretical advantages: - A smaller instrument diameter with potentially a lower risk of uterine perforation and cervical laceration during the dilatation procedure, - The use of physiological serum, eliminating the risk of neurological toxicity of glycine, - The risk of electrical accident is canceled (internal or external burns due to leakage current), - A decreased risk of air embolism, due to the absence of bubbles' production, - The instrument is always under visual control, the perforation risk by the active instrument is therefore very limited, - The vision is not obscured by the fragments or by the bubbles, - The treatment of pre-ostial pathologies, not always easy in classical resections, could be facilitated, - the absence of thermal effect, and therefore a potentially lower endometrial aggression, is interesting in women with reproductive desire, - Absence of chips management, limiting the entry and exit movements in the uterine cavity, improving the vision, reducing the infectious and traumatic risks, specially uterine perforation and air embolism, - Morcellation could preserve tissues for histological analysis of possible malignancy (compared to techniques using heat, coagulation, vaporization), - Easy learning in comparison to the time-consuming learning of classical hysteroscopic resection, - Generated additional cost could be partly amortized by reducing operating time and complications. It seemed useful to study this new technology. The primary purpose was to compare the time of hysteroscopic treatment of uterine polyps between a hysteroscopic morcellator the UNIDRIVE S III / DrillCut-X II-GYN-Shaver (Integrated Bigatti Shaver IBS), Storz®, and a conventional resectoscope. The secondary purposes were to compare the efficiency, complications and comfort of these techniques.

NCT ID: NCT02470416 Completed - Polyps Clinical Trials

Prevalence of Small Bowel Polyps in Patients With Sporadic Duodenal Adenomas

SPIDA
Start date: October 2015
Phase: N/A
Study type: Interventional

Little is known about the prevalence of small bowel polyps in patients with sporadic Duodenal/Ampullary polyps. The investigators aim to investigate the prevalence of small bowel polyps in patients with sporadic (ie not related to FAP or PJS) duodenal/ampullary adenomas by performing small bowel capsule endoscopy and comparing the results to those acquired from a control cohort undergoing VCE for accepted indication at our centre.

NCT ID: NCT02407925 Completed - Colonoscopy Clinical Trials

Implementation of Optical Diagnosis for Diminutive Polyps Amongst Endoscopists: Training and Long-term Quality Assurance

DISCOUNT2
Start date: January 1, 2015
Phase: N/A
Study type: Observational

In this study, Dutch gastroenterologists who are certified for performing colonoscopies on FIT-positive patients in the Dutch population screening program are trained in optical diagnosis with validated methods. After this training, an ex- and in-vivo test phase leads to "accreditation" and endoscopists will be observed in their optical diagnosis for 1 year. During this year, half of the endoscopists will be randomized towards 3-monthly feedback and the other half will receive feedback on their results after 1 year. The endoscopic prediction of endoscopists on polyp histology will be compared to histopathological outcome.