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Polyps clinical trials

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NCT ID: NCT00247923 Completed - Endometrial Cancer Clinical Trials

Endometrial Polyps: Pathophysiology and Clinical Consequences

Start date: October 2005
Phase: N/A
Study type: Interventional

The aim of these studies is to study the natural history, the symptoms of, as well as the effect of hysteroscopic resection of endometrial polyps. Furthermore, another aim is to study new diagnostic techniques to differentiate between malignant and benign endometrial polyps.

NCT ID: NCT00234650 Completed - Polyps Clinical Trials

Adenoma Detection Rate With Position Change at Colonoscopy

Start date: October 2005
Phase: N/A
Study type: Interventional

The hypothesis to be tested is that position changes during the withdrawal phase of colonoscopy leads to a higher adenoma (polyp) detection rate because of better distension of the colon. Since adenomas are precancerous lesions the enhanced adenoma detection will increase the success of colorectal cancer screening programmes. This study will provide evidence for the value of position changes and encourage endoscopist to adopt position change as a routine in their practice. May 2007: protocol amendment to include additional prospective analysis using High Definition TV (HDTV).

NCT ID: NCT00208793 Completed - Clinical trials for Colorectal Adenomatous Polyps

Calcium and Vitamin D vs Markers of Adenomatous Polyps

CaDvMAP
Start date: May 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to test whether calcium and/or vitamin D supplementation favorably affects a set of biomarkers of risk for colon cancer in persons who are at higher than average risk for colon cancer (ie, have already undergone the removal of adenomatous polyps, which are known to be precursors to developing colon cancer).

NCT ID: NCT00153816 Completed - Colorectal Cancer Clinical Trials

Vitamin D/Calcium Polyp Prevention Study

Start date: July 2004
Phase: Phase 2/Phase 3
Study type: Interventional

Extensive experimental and observational data suggest that intake of calcium and of vitamin D exert protective effects on colorectal neoplasia. Building on their previous work, the investigators will investigate the chemopreventive effect of vitamin D in the large bowel, to study whether calcium with vitamin D is more effective than calcium alone, and to confirm their positive finding regarding calcium. The goal of this study is the development of chemopreventive combinations that will reduce risk of colorectal neoplasia sufficiently to permit the lengthening of surveillance intervals in most patients and to clarify important issues regarding the mechanisms of colorectal carcinogenesis and chemoprevention.

NCT ID: NCT00145015 Completed - Colorectal Cancer Clinical Trials

FishGastro Study: Fish Consumption and Gastro-Intestinal Health

Start date: December 2004
Phase: N/A
Study type: Interventional

The purpose of the study is to determine whether increasing the dietary intake of n-3 fatty acids by the consumption of oil-rich fish reduces the risk of developing colorectal cancer.

NCT ID: NCT00114842 Completed - Colorectal Cancer Clinical Trials

Magnetic Resonance (MR) Colonography With Fecal Tagging

Start date: March 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if MR colonography with fecal tagging is better using air or water for distension of the colon. Patients referred to colonoscopy are offered MR colonography before colonoscopy. Two days before colonography, patients ingest a 200 ml Barium sulfate solution 2% four times a day, which will render fecal masses "invisible" on the following MR colonography. Air or water (randomised trial) is used for distension of the colon. The examinations are evaluated by two independent blinded readers.