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Polyps clinical trials

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NCT ID: NCT01461564 Completed - Polyps Clinical Trials

Carbon Dioxide During Screening Unsedated Colonoscopy

Start date: January 2010
Phase: Phase 4
Study type: Interventional

Colonoscopy is currently most effective procedure used for detecting colon cancer especially in the early stages. Screening colonoscopies are performed in the symptom-free patients at risk of familial colon cancer. During colonoscopy air commonly used to insufflate the bowel may be retained after the procedure causing pain and discomfort to the patients. One of the methods used to reduce pain and discomfort is insufflation of carbon dioxide (CO2) instead of air during colonoscopy. Aim of the study is evaluation of the use of carbon dioxide insufflation during colonoscopy.

NCT ID: NCT01439087 Completed - Colonic Polyps Clinical Trials

Optical Frequency Domain Imaging for Assessing Colonic Polyps

Start date: July 2009
Phase: N/A
Study type: Interventional

The goal of this research is to conduct a pilot clinical study to image colonic polyps with the intent to evaluate the potential use of Optical Frequency Domain Imaging (OFDI) to identify the extent of invasion (if present), differentiate between hyperplastic polyps and adenomas, and identify serrated polyps.

NCT ID: NCT01437631 Completed - Clinical trials for Polyp of Large Intestine

EFficacy of Prophylactic Clip Application in Decrease of Immediate Postpolypectomy Bleeding and Delayed Postpolypectomy Bleeding After Colonoscopic Removal for a Large Pedunculated Polyps

Start date: September 1, 2011
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the efficacy of prophylactic clip application after colonoscopic removal for a large pedunculated polyp (> 1cm) in preventing immediate postpolypectomy bleeding (IPPB) and delayed postpolypectomy bleeding (DPPB).

NCT ID: NCT01430208 Completed - Polyps Clinical Trials

A New Alternative to Traditional Hysteroscopy

Start date: January 2010
Phase: N/A
Study type: Interventional

Hysteroscopy is a procedure designed for the diagnosis and the treatment of intra-uterine diseases. The development of smaller hysteroscopes allowed to change the approach to the intra-uterine lesions unifying the diagnostic and operative time. Recently Gubbini et al. developed a mini-resectoscope feasible for "see&treat" hysteroscopy. The objective of the study is to compare the new 16 Fr mini28 resectoscope by Gubbini with Traditional 22 Fr resectoscope and Bettocchi 15 Fr hysteroscope for the treatment of uterine cavitary lesions. The investigators enrolled 401 women affected by endometrial polyps and/or G0 myomas, randomly allocated to receive the treatment with traditional resectoscope (127 women), with mini-resectoscope by Gubbini (142 women) and Bettocchi hysteroscope (132 women). Operating time, distension media delivered, dismiss time and discomfort experienced were recorded.

NCT ID: NCT01415817 Completed - Colorectal Polyps Clinical Trials

Endoscopic Quality Improvement Program

EQUIP
Start date: August 2010
Phase: N/A
Study type: Interventional

Effective colorectal cancer (CRC) screening relies on early identification and removal of both polypoid and non-polypoid lesions with neoplastic potential. The investigators hypothesize that an intensive training program designed to enhance both recognition and classification of lesions with neoplastic potential, will result in an increase in non-polypoid adenoma detection in addition to and independent of an increase in overall adenoma detection rates.

NCT ID: NCT01395173 Completed - Colonic Polyp Clinical Trials

Position Changes During Colonoscope Withdrawal and Polyp Detection

Start date: July 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether position changes during colonoscope withdrawal affects polyp detection rate. We hypothesize that positions change during scope withdrawal will increase polyp detection rate.

NCT ID: NCT01386125 Completed - Nasal Polyps Clinical Trials

A Study of the Effectiveness and Safety of Mometasone Furoate Nasal Spray (MFNS, SCH 032088) for the Treatment of Nasal Polyps (P05604)

Start date: June 2011
Phase: Phase 3
Study type: Interventional

This study will evaluate the effectiveness and safety of MFNS in improving nasal congestion/obstruction and in reducing bilateral nasal polyps.

NCT ID: NCT01368731 Completed - Clinical trials for Adenomatous Polyp of Large Intestine

Prophylactic Coagulation for the Prevention of Bleeding in Endoscopic Mucosal Resection of Large Sessile Colonic Polyps

Start date: May 2011
Phase: N/A
Study type: Interventional

The hypothesis of this study is that prophylactic coagulation therapy with coagulation forceps to visible vessels within the mucosal defect for colonic Endoscopic Mucosal Resection (EMR) will reduce the rate of delayed bleeding when compared with current established standard EMR technique.

NCT ID: NCT01354873 Completed - Colon Polyps Clinical Trials

Colorectal Polyp Discrimination Using High-Definition Narrow Band Imaging

Start date: January 2011
Phase: N/A
Study type: Observational

The investigators seek to compare the accuracy of the existing colonoscope model to determine the magnitude of the improvement the investigators can expect in polyp discrimination as neoplastic or non-neoplastic.

NCT ID: NCT01310699 Completed - Colorectal Cancer Clinical Trials

Study of Flat Polyp Detection Using New Narrow Band Imaging (NBI) Compared to White Light Colonoscopy - The FIND FLAT Colonoscopy Study

NBI
Start date: January 2013
Phase: N/A
Study type: Interventional

We hypothesize that high definition narrow band imaging (NBI) colonoscopy compared to high definition white light colonoscopy will detect an increased number of nonpolypoid (flat and depressed) colorectal neoplasm.