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Clinical Trial Summary

The purpose of this study is to determine whether double-dose Ranibizumab are effective to regress the polyps and benefit to the visual outcome in the polypoidal choroidal vasculopathy (PCV).


Clinical Trial Description

Recently, it's reported that intravitreal high dose Lucentis®(Ranibizumab) could benefit to both regression of the polyps and the relief of macular edema in PCV patients. Since it was a single arm prospective study with a relatively small sample size, randomized clinical trials were needed to confirm the efficacy of high dose Ranibizumab in PCV treatment. In this study, the investigator will compare the efficacy of double-dose (1mg, 3+prn) Raibizumab with regular dose (0.5mg, 3+prn) for PCV treatment. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02769169
Study type Interventional
Source Sun Yat-sen University
Contact
Status Terminated
Phase Phase 2/Phase 3
Start date August 1, 2018
Completion date December 15, 2018

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