Polypharmacy Clinical Trial
— OLD-NH-IDeIOfficial title:
Opportunities and Limits to Deprescribing in Nursing Homes: Randomised, Controlled Trial of an Individual Deprescribing Intervention for Nursing Homes Residents.
Verified date | April 2021 |
Source | University of Geneva, Switzerland |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study will evaluate the effects of a pharmacist-led, deprescribing-focused medication review on the use of inappropriate medications by nursing home residents
Status | Completed |
Enrollment | 62 |
Est. completion date | August 22, 2019 |
Est. primary completion date | August 22, 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 65 Years and older |
Eligibility | Inclusion Criteria: - Take 5 or more prescribed drugs daily; - Reside in the Nursing Home since at least 4 months. Exclusion Criteria: - Physician judges that discussing deprescribing with them risks destabilising them. |
Country | Name | City | State |
---|---|---|---|
Switzerland | Centre de Pharmacie Communautaire | Lausanne | Vaud |
Lead Sponsor | Collaborator |
---|---|
Anne Niquille |
Switzerland,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Number of Deaths | Number of deaths | 4 months | |
Other | Number of Participants Hospitalized | Number of participants hospitalized at any time during the study | 4 months | |
Other | Days Spent in Hospital | Average number of days spent in hospital during the study period | 4 months | |
Other | Number of Falls Per Participant | Average number of falls during the study period | 4 months | |
Other | Number of Participants Who Fell | Number of participants who fell at least once during the study period | 4 months | |
Other | Number of Falls in Participants That Fell at Least Once | 4 months | ||
Other | Number of Days Spent With Physical Restraints | 4 months | ||
Primary | Number of Inappropriate Medication at Follow-up | Number of inappropriate medications prescribed at follow-up, assessed using the French translation of STOPP v2. | 4 months | |
Secondary | Number of Potentially Inappropriate DDDs Prescribed to Participants at Follow-up | Appropriateness assessed using the French translation of STOPP v2; DDD defined by WHO. | 4 months | |
Secondary | Number of Chronic Drugs Prescribed to Participants | Number of Chronic Drugs Prescribed to Participants | 4 months | |
Secondary | Number of Chronic DDDs Prescribed to Participants | Number of chronic DDDs prescribed to participants | 4 months | |
Secondary | Number of New Drugs Prescribed as a Result of the Intervention | This outcome was not analysed | 4 months | |
Secondary | Health-related Quality of Life | The EuroQol 5-Dimensions 5-Levels (EQ-5D-5L) tool was used to assess quality of life; this tool includes
a visual analog scale, ranging from 0 to 100, 100 indicating "the best health you can imagine" and 0 "the worst health you can imagine". Higher results indicate an higher quality of life. 5 questions, each with 5 possible answers. Using a valuation set, the answers to individual questions were transformed in a numeric index value for each participants, with a maximum of 1 and an infinitely low minimum. Higher values indicates higher perceived health-related quality of life. |
4 months | |
Secondary | Number of Common Drug-related Complaints at Follow-up | Number of common drug-related complaints at follow-up | 4 months |
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