Polypharmacy Clinical Trial
Official title:
Impact of a Deprescribing Intervention on Nursing Home Residents: a Randomized Controlled Trial
This study will develop, implement and evaluate a deprescribing initiative at a Canadian Long
Term Care (LTC) Facility. Residents currently undergo an annual medication review as part of
the clinical pharmacy services provided in the LTC facility. For this study, eligible
residents will be randomized to receive either a deprescribing focused medication review or
usual care.
The deprescribing focused medication therapy assessments will be done on half of the 143
residents residing on the second and third floors of the facility. The other half of
residents will serve as the control group and continue to receive their annual medication
review and regular care from the attending physicians and nurses.
The deprescribing intervention will be delivered by final year pharmacy students completing
their practice experiences, under the supervision of clinical pharmacists at the LTC facility
and clinical pharmacists from Memorial University's Medication Therapy Services (MTS) Clinic.
Currently the clinic has a well developed procedure for providing in depth medication therapy
reviews for residents of the community, upon referral by their primary care physician.
Students will adapt this model of medication review to have a stronger deprescribing focus
and be applicable to elderly residents of a LTC facility. The intervention will consist of an
in depth medication therapy review with a focus on identifying any medications that may no
longer be required or are deemed to be inappropriate or potentially unsafe in the elderly
based on currently guidelines/criteria. The students will work closely with members of the
resident's care team on a daily basis, as well as the resident and their family, to develop
and implement a deprescribing plan.
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