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Polycystic Ovary Syndrome and BETATROPHIN

Obesity Clinical Trial

Official title:
Can the Betatrophin be a Reliable Marker of Insulin Resistance in Normal Weight and Overweight Women With Polycystic Ovary Syndrome?

Clinical Trial Summary

This is an original study giving an information about the association body mass index, polycystic ovary syndrome and betatrophin.

Clinical Trial Description

Introduction: Betatrophin is a protein hormone which has a significant role in glucose homeostasis and lipid metabolism. The aim of this study is to compare the levels of serum betatrophin in overweight and normal weight women with PCOS.

Material and Method: Thirty-five patients normal weight women with PCOS (BMI<25) and 38 obese women with PCOS (BMI≥25) were included in this prospective, cross-sectional study. Patients were selected according to Rotterdam criteria. Serum betatrophin levels were studied by ELISA method and then compared between these two groups besides the following additional parameters as waist circumference/hip circumference ratio, fasting blood glucose, 75 g OGTT (oral glucose tolerance test) results and HOMA-IR levels. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04448730
Study type Observational
Source Kayseri Education and Research Hospital
Contact
Status Completed
Phase
Start date January 1, 2018
Completion date December 30, 2019
View Details
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