Polycystic Ovary Syndrome (PCOS) Clinical Trial
Official title:
Effects of Micronized Trans-resveratrol Treatment on Clinical, Endocrine, Metabolic and Biochemical Parameters of Women With Polycystic Ovary Syndrome: Placebo-controlled Randomized Single-blind Study
The purpose of this study is to determine whether micronized trans-resveratrol improves clinical (excessive hair, menstrual cycle), endocrine (androgens)and metabolic (lipids, markers of systemic inflammation) in women with polycystic ovary syndrome (PCOS).
Status | Not yet recruiting |
Enrollment | 40 |
Est. completion date | December 2014 |
Est. primary completion date | December 2013 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years to 40 Years |
Eligibility |
Inclusion Criteria: - PCO - Androgen Excess Society criteria: hyperandrogenism (hirsutism) / hyperandrogenemia (testosterone >70ng/dl) and/or oligomenorrhea (<8 spontaneous menses per year) and/or polycystic ovarian morphology on ultrasound - Normal prolactin, TSH, 17-OH progesterone - No evidence of androgen producing malignancy, Cushing's syndrome or acromegaly - Age 18-40 Exclusion Criteria: - Use of oral contraceptives and/or other steroid hormones 3 months prior to the study |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Poland | Poznan University of Medical Sciences | Poznan |
Lead Sponsor | Collaborator |
---|---|
Poznan University of Medical Sciences | University of California, Davis |
Poland,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | testosterone serum concentration | 3 month therapy | No |
Status | Clinical Trial | Phase | |
---|---|---|---|
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