Polycystic Ovarian Syndrome Clinical Trial
Official title:
A Randomized Control Trial to Compare the Euploid Rate of Blastocyst Between the PPOS (Progestin-primed Ovarian Stimulation) Protocol and the Gonadotropin-releasing Hormone (GnRH) Antagonist Protocol in Women With PCOS (Polycystic Ovary Syndrome) Undergoing PGT-A (Preimplantation Genetic Testing for Aneuploidy)
This randomized trial aims to compare the euploid rate of blastocysts between PPOS (progestin-primed ovarian stimulation) and GnRH (gonadotrophin releasing hormone) antagonist protocols in patients with PCOS (polycystic ovary syndrome) undergoing PGT-A (preimplantation genetic testing for aneuploidy). Infertile women with PCOS will be recruited for study after explanation and counseling if they fulfill the inclusion criteria and do not have the exclusion criteria. Eligible women will be randomised into one of the two groups: Antagonist group: Women will receive antagonist once subcutaneously daily from day 6 of ovarian stimulation till the day of the ovulation trigger. PPOS group: Women will receive oral MPA (medroxyprogesterone acetate)10mg qd from Day 3 till the day of ovulation trigger. The primary outcome is the euploidy rate of blastocysts.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT02244567 -
Effect of Metformin Therapy on Serum Under-carboxylated Osteocalcin Levels in Hyperandrogenic Lean Polycystic Ovarian Syndrome Women
|
Phase 1 | |
Completed |
NCT01672801 -
Nimodipine to Prevent LH Surge During Ovulation Induction: Blinded Placebo-controlled RCT
|
N/A | |
Completed |
NCT01653743 -
Trial to Assess the Clinical Efficacy and Safety of MSJ-0011 in Inducing Ovulation in Anovulatory or Oligo-ovulatory Japanese Women
|
Phase 3 | |
Completed |
NCT00579540 -
Compare Effects of Flax Seed Oil, and Fish Oil on Blood Sugar Levels
|
N/A | |
Terminated |
NCT05084274 -
Optimising Preconceptual Health in Subfertile PCOS Patients Using a Lifestyle Modification Program
|
N/A | |
Completed |
NCT03717935 -
Oral Amino Acid Nutrition to Improve Glucose Excursions in PCOS
|
N/A | |
Withdrawn |
NCT01716429 -
Healthy Eating for Reproductive Health: Greenville
|
N/A | |
Active, not recruiting |
NCT02896452 -
Astronaut Vision Issues in a Ground Analog Population: Polycystic Ovary Syndrome
|
||
Recruiting |
NCT05146063 -
LNK in Polycystic Ovary Syndrome With Insulin Resistance
|
||
Recruiting |
NCT06303219 -
Effects of Traditional Moderate Intensity Training and High Intensity Interval Training in Polycystic Ovarian Syndrome
|
N/A | |
Completed |
NCT02869750 -
The Relationship Between Adipokines, Obesity and Insulin Resistance in Women With Polycystic Ovarian Syndrome
|
||
Completed |
NCT01237106 -
In Vitro Maturation (IVM) for Polycystic Ovary Syndrome (PCOS)
|
N/A | |
Completed |
NCT01185704 -
Analysis of Two Therapeutic With Cetrotide® in Polycystic Ovarian (PCO) Women in Assisted Reproductive Technology (ART)
|
Phase 3 | |
Recruiting |
NCT04029805 -
Evaluation of a Combination of a Plant Extract and a Probiotic on Glucidic Metabolism in Women With PCOS and High Insulin Levels
|
Phase 1/Phase 2 | |
Completed |
NCT01675843 -
Ovarian Stimulation and Intrauterine Insemination in Women With Polycystic Ovarian Syndrome
|
Phase 4 | |
Completed |
NCT01577017 -
The Effects of Letrozole And Clomiphene Citrate For Induction of Ovulation In Polycystic Ovarian Syndrome(PCOS)
|
Phase 3 | |
Completed |
NCT00478504 -
Letrozole Versus Clomifene Citrate for Ovulation Induction
|
Phase 4 | |
Completed |
NCT05215223 -
Effect of Whole Body Vibration on Insulin Resistance in Females With Polycystic Ovarian Syndrome
|
N/A | |
Completed |
NCT03358199 -
LOD Before IVF/ICSI in PCOS Patients With High AMH
|
N/A | |
Completed |
NCT02436226 -
Use of Low Dose of HCG During Ovulation Induction With CC in Women With CC Resistant PCOS
|
Phase 4 |