Insulin Resistance Clinical Trial
Official title:
Evaluation of the Effect of a Combination of a Plant Extract (BSL_EP044) and Lactobacillus BSL_PS6 on Glucidic Metabolism in Women Suffering From Polycystic Ovary Syndrome and High Insulin Levels
The aim of the present study is to evaluate the effect of the combination of a plant extract (BSL_EP044) and Lactobacillus BSL_PS6 on parameters of the glucidic metabolism, anthropometric parameters, hormonal levels and the menstrual cycle in women with polycystic ovary syndrome and high insulin levels.
Polycystic ovary syndrome (PCOS) is the most prevalent endocrinopathy in women, affecting
4-15% of those who are of childbearing age. It is a complex and heterogeneous disease in
which the gynecological disorder coexist with metabolic problems such as insulin resistance.
The beneficial effect of the extract plant BSL-EP044 on glycemic metabolism in women with
PCOS is widely studied and demonstrated and Lactobacillus BSL_PS6 appears to exert a
synergistic effect by supplementing the effect of BSL-EP044. The hypothesis of our study is
that the addition of the probiotic strain Lactobacillus BSL_PS6 to extract plant BSL-EP044
treatment may improve the beneficial effect of this one on insulin resistance and other
metabolic alterations related to PCOS.
The main objective of the present study is to evaluate the effect of the combination of a
Plant Extract (BSL_EP044) and Lactobacillus BSL_PS6 on parameters related to glycemic
metabolism in women with polycystic ovary syndrome and high insulin levels.
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