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Erosive Osteoarthritis of the Hands: Treatment by Methotrexate Versus Placebo — ADEM  

Polyarthritis Clinical Trial

Official title:
Erosive Osteoarthritis of the Hands: Treatment by Methotrexate Versus Placebo - Assessment of Structural and Clinical Action of Magnetic Resonance Imaging

Clinical Trial Summary

Interest of methotrexate in inflammatory rheumatisms was demonstrated since several years.

At present time,there is no effective treatment against digital arthritis. The investigators purpose to measure the efficacy of methotrexate on digital arthritis.

In this aim, two groups were compared. The first group receive 10mg/week of methotrexate administered in one shot (every Monday for example)during 12 months. The second group receive 10mg/week of placebo according to the same procedure

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01068405
Study type Interventional
Source Centre Hospitalier Universitaire de Nice
Contact Christian H ROUX, PhD
Email roux.cr@chu-nice.fr
Status Recruiting
Phase Phase 3
Start date March 2010
Completion date March 2012
View Details
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