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Poisoning clinical trials

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NCT ID: NCT05744752 Active, not recruiting - Lead Poisoning Clinical Trials

Effects of Allium Sativum and Moringa Oleifera Extract on Dental Enamel

Start date: December 19, 2022
Phase: N/A
Study type: Interventional

Primary objective is to observe the effects of lead on dental enamel of rabbit by measuring; - Structural and morphological change by SEM, AFM - Elemental composition by SEM-EDX - Molecular composition and hydroxyapatite crystal changes by Raman Spectroscopy - Blood parameters by serum analysis Secondary objectives includes - To compare the protective effects of Allium sativum and Moringa oleifera on dental enamel defects due to lead - To determine the beneficial effects of AS and MO extract in remineralization of dental enamel.

NCT ID: NCT05247229 Active, not recruiting - Clinical trials for Shellfish Poisoning, Paralytic

Prevention of Paralytic Shellfish Poisoning in Subsistence Shellfish Harvest Communities of Southeast Alaska

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this tribally co-led community-based participatory research in partnership with Sitka Tribe of Alaska is to help prevent Paralytic Shellfish Poisoning (PSP) in children of Southeast Alaska. The investigators assess whether an education intervention leads to changes in participants' planned behaviors related to clam harvesting that may reduce risks of exposure to shellfish toxins. This project includes both a human subjects research component (this clinical trial) and a non-human environmental research component. In the non-human component, the tribe is monitoring for toxins in shellfish (including shellfish provided by people with data originally collected as a non-research service), and testing water for the presence of algae that make the toxin. The human subjects component involves age-appropriate K12 educational outreach in partnership with the Sitka School District, Hoonah City Schools, and Juneau School District, including a middle school after-school non-credit educational program coupled to a research program in Sitka, AK and Juneau, AK and a middle school during school elective educational program coupled to a research program in Hoonah, AK. Middle school students participating in the program will attend the program with several units designed to teach cultural practices, strengthen competencies toward Alaska science state standards, and evaluate shellfish consumption-related risk behaviors, while affirming traditional culture.

NCT ID: NCT04192526 Active, not recruiting - Toxicity;Chemical Clinical Trials

Serum Cholinesterase Level in Aluminum Phosphide Poisoning, the Possible Proposing Role of Atropin & Pralidoxime

ALPH
Start date: December 1, 2019
Phase:
Study type: Observational

Metal phosphides are widely used as a rodenticide and insecticide and poisoning with these substances has a very high mortality. The aim of this study was to evaluate the butyrylcholinesterase (BuCh) level in poisoning with metal phosphides.

NCT ID: NCT04191265 Active, not recruiting - Cardiotoxicity Clinical Trials

Cardiotoxicity of Aluminum Phosphide Poisoning; Tropinin and CKmb as Early Biomarkers

Start date: December 5, 2019
Phase:
Study type: Observational

Aluminum phosphide (AlP) or rice tablet is a cheap pesticide. When it comes in contact with acid (gastric acid) or moisture, it releases phosphine (PH3) gas. The heart,lungs, liver are the main targets in acute Aluminum phosphide (AlP) poisoning. Most deaths occur due to cardiovascular toxicity.

NCT ID: NCT03925025 Active, not recruiting - Pesticide Poisoning Clinical Trials

Effectiveness of Calcium Channel Blockade for OP and Carbamate Pesticide Poisoning

CCBOC
Start date: June 11, 2020
Phase: Phase 3
Study type: Interventional

This study evaluates whether the addition of intravenous magnesium sulphate or nimodipine to standard therapy (supportive care plus for all patients atropine and, for OP insecticide poisoned patients, pralidoxime) benefits patients after acute anticholinesterase self-poisoning with OP or carbamate insecticides.

NCT ID: NCT03725592 Active, not recruiting - Arsenic Poisoning Clinical Trials

Strong Heart Water Study

SHWS
Start date: July 2, 2018
Phase: N/A
Study type: Interventional

Develop and evaluate the effectiveness of multi-level participatory interventions in reducing arsenic exposure among American Indian (AI) communities from North and South Dakota who participated in the Strong Heart Study (SHS).

NCT ID: NCT03651778 Active, not recruiting - Drug Toxicity Clinical Trials

GHB Poisoning and Poisoning Induced by Others

Start date: September 1, 2018
Phase:
Study type: Observational

Patients with suspected GHB poisoning presenting to Oslo Accident and Emergency Outpatient Clinic (Oslo Legevakt) or a hospital in Oslo (Oslo University Hospital Ullevål, Diakonhjemmet, Lovisenberg) will be included. Oral fluid and blood tests will be analyzed for recreational drugs. Clinical course will be charted, as well as treatment in the ambulance, emergency outpatient clinic and hospital to find predictors for when hospitalization is required. In the second part of the study the investigators will analyze urine and blood samples from patients presenting to the Oslo Accident and Emergency Outpatient Clinic (Oslo Legevakt) with suspected substance poisoning induced by others, for toxic agents.

NCT ID: NCT03481192 Active, not recruiting - Suicide Clinical Trials

Voluntary Drug Poisoning by Psychoactive Molecules: Identify Cognitive Markers

IMG-COG
Start date: January 2, 2018
Phase: N/A
Study type: Interventional

To identify in patients admitted for Voluntary drug poisoning (IMV) by psychoactive substances, T1 predictors of T2 recall of psychiatric interview and care project.

NCT ID: NCT02866266 Active, not recruiting - Clinical trials for Opioid-related Disorders

ER/LA Opioid Surveillance for Emergency Department Visits and Hospitalizations for Overdose and Poisoning

Start date: n/a
Phase: N/A
Study type: Observational

Study to evaluate the impact of the ER/LA opioid REMS program on the incidence of Emergency Department visits and hospitalizations for overdose/poisoning and death among patients prescribed ER/LA opioid analgesics.