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Poisoning clinical trials

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NCT ID: NCT02986763 Completed - Pesticide Poisoning Clinical Trials

Evaluation of Pesticide Exposure in the General Population

SIGEXPOSOME
Start date: June 2015
Phase: N/A
Study type: Observational

An association has been suggested with several diseases including cancer and IARC has classified several pesticides as carcinogenic, probably carcinogenic. There is a need for a better characterisation of environmental pesticides exposures and identification of suitable biomarkers of exposure and effect. A better understanding of the impact of pesticide exposure on metabolomic, transcriptomic and epigenetic changes, is essential to strengthen epidemiological hypotheses on the association with several cancer types. The main objective of the project is to validate a GIS (geographic information system) based method to assess environmental pesticide exposures, using environmental (contamination of housedust) and biological (blood and urine samples) measures. The project aims further to investigate a potential link between housedust contamination and biological measures in healthy non-smoking male residents and explore the impact of environmental pesticide exposure on metabolomics, transcriptomic and epigenetic parameters.

NCT ID: NCT02950701 Completed - Clinical trials for Carbon Monoxide Intoxication

Suspected Cases of Carbon Monoxide Poisoning

Start date: November 2016
Phase:
Study type: Observational

The purpose of this study is to collect non-invasive opportunity sample data in suspected or known cases of carbon monoxide poisoning.

NCT ID: NCT02908581 Completed - Clinical trials for Chronic Arsenic Poisoning

Effect of Iron and Folic Acid on Skin Fungal Pattern in Patients With Arsenicosis

Start date: June 2016
Phase: Phase 2
Study type: Interventional

This study will be conducted to observe any change in fungal pattern on skin of arsenicosis patients before and after administration of iron (150 mg) and folic acid (0.5 mg) tablets.

NCT ID: NCT02877498 Completed - Clinical trials for Invasive Mechanical Ventilation

A Study to Compare Adaptive Support Ventilation vs. Volume Controlled Ventilation for Management of Respiratory Failure in Patients With Neuroparalytic Snake Envenomation

ASV vs VCV in
Start date: December 2016
Phase: N/A
Study type: Interventional

Neuroparalytic snake envenomation results in severe muscle weakness and respiratory failure. Treatment requires administration of anti-snake venom and supportive care in the form of invasive mechanical ventilation. Whether using adaptive support ventilation (a closed loop mode of ventilation) in comparison to volume controlled ventilation will shorten the duration of ventilation remains undetermined. The current study is planned to compare adaptive support ventilation (ASV) mode of ventilation versus volume controlled ventilation (VCV) during invasive mechanical ventilation for the management of respiratory failure secondary to neuroparalytic snake envenomation.

NCT ID: NCT02838303 Completed - Clinical trials for Organophosphate Poisoning

The Use of Self-reported Symptoms as a Proxy for Acute Organophosphate Poisoning Among Nepali Farmers

Start date: September 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate self-reported symptoms as a proxy for acute organophosphate poisoning by examining self-reported acute organophosphate poisoning symptoms and PchE activity in response to occupational acute organophosphate exposure among farmers in Nepal.

NCT ID: NCT02580760 Completed - Clinical trials for Injection Site Extravasation

Transgender, Silicone and Blood Smear

TSBS
Start date: July 2015
Phase: N/A
Study type: Observational

This cross-sectional monocentric study will describe transgender men transitioning into women and who had cosmetic silicone injection. The principal objective is to estimate the prevalence of Transgender with circulating monocytes containing silicone vacuoles in blood smears among Male to Female Transgender population with a history of cosmetic silicon injections. The secondary objectives are to describe the transgender population, to describe the quantity of silicone in vacuoles of circulating monocytes, and the association between dermatological complications (inflammatory and not inflammatory) and several clinical and biological characteristics (HIV status, level of immunosuppression, inflammatory syndrome, quantity of silicone which was injected , silicone quantity in blood smears).

NCT ID: NCT02553070 Completed - Poisoning Clinical Trials

Health Professions Students and Faculty Perceptions of Poisoning Severity

Start date: September 2015
Phase: N/A
Study type: Observational

Inaccurate perceptions of the severity of an exposure may result in unnecessary visits to the Emergency Department or Health Care Facility which can result in crowding of Emergency Departments, unnecessary utilization of valuable health care resources, unnecessary treatments, and or mistakes / errors resulting in harm to the patient. Inaccurate perceptions about the severity of an exposure can result in delays in proper evaluation and treatment resulting in harm or in some cases death of the patient.

NCT ID: NCT02486289 Completed - Mercury Poisoning Clinical Trials

Pilot Proof of Concept Study of NBMI Treatment of Mercury Intoxication

NBMI
Start date: August 2015
Phase: Phase 2
Study type: Interventional

A randomized, placebo controlled, double blind proof of concept study of NBMI in treatment of mercury intoxication.

NCT ID: NCT02429921 Completed - Arsenic Poisoning Clinical Trials

High-selenium Lentils Versus Arsenic Toxicity

Start date: October 2015
Phase: N/A
Study type: Interventional

About 45 million people in Bangladesh are chronically exposed to unacceptable levels of arsenic in their drinking water. Chronic arsenic poisoning leads to cancers, and vascular diseases. This dietary trial intends to test the potential of high-selenium lentils, consumed as lentil soup, in reducing the arsenic body burden in an exposed Bangladeshi population, and in improving the overall health status. Arsenic-exposed families will be assigned to one of two groups. One group will eat lentils (50g/person/day) that are naturally high in selenium, the other group will receive lentils with low selenium content. This 6 months trial is randomized and double-blinded.

NCT ID: NCT02415712 Completed - Clinical trials for Ethylene Glycol Poisoning, Methanol Poisoning

Specified Drug-use Survey of Fomepizole Intravenous Infusion (All-case Surveillance)

Start date: January 27, 2015
Phase:
Study type: Observational

The objective of this survey is to evaluate the safety and efficacy of fomepizole intravenous infusion in Japanese patients with ethylene glycol and methanol poisonings in daily medical practice.