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Pneumoperitoneum clinical trials

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NCT ID: NCT02129959 Not yet recruiting - Laparoscopy Clinical Trials

Cardiovascular Effects of the Degree of Head-down and Pneumoperitoneum During Laparoscopy

Start date: May 2014
Phase: N/A
Study type: Observational

The aim of this study is to observe the cardiovascular effects of the degree of head-down angle and pneumoperitoneum during laparoscopic procedure using by the fourth version Vigileo-Flotrac system.

NCT ID: NCT02114164 Completed - Prostate Cancer Clinical Trials

Study of Carbon Dioxide Exchange Patterns During Robotic Prostatectomies

Start date: August 2016
Phase: N/A
Study type: Interventional

The AirSeal® System will allow for lower carbon dioxide (CO2) absorption rates than the standard Endopath System.

NCT ID: NCT02079337 Completed - Clinical trials for Neuromuscular Blockade

Validation of Subjective Rating Scales Used to Assess Surgical Conditions in Abdominal Surgery

Start date: November 2013
Phase: Phase 4
Study type: Interventional

Use of neuromuscular blockade (NMB) may improve the surgical work space in patients scheduled for laparoscopic surgical cases (e.g. hysterectomy, ovarian cystectomy, myomectomy). Clinical studies investigating this question often use a numerical or verbal rating scale for subjective evaluation of the surgical workspace. However, no good subjective rating scale have been developed or validated. Neither have possible inter-individual differences in use of such subjective scales been described. Purpose: The aim of this study is to validate different subjective rating scales to determine which scale is most useful among surgeons.

NCT ID: NCT02013596 Completed - Clinical trials for Renal Function Disorder

Transcutaneous Electrical Acupoint Stimulation(TEAS) for Hepatic and Renal Dysfunction After Pneumoperitoneum

TRIP
Start date: December 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effect of TEAS pretreatment and treatment on hepatic and renal dysfunction induced by pneumoperitoneum in patients undergoing laparoscopic surgeries.

NCT ID: NCT02004925 Completed - Pneumoperitoneum Clinical Trials

Accuracy of Ultrasonography for the Diagnosis of Pneumoperitoneum in the Emergency Department

Start date: January 2014
Phase: N/A
Study type: Observational

Pneumoperitoneum could be due to life threatening conditions and its quickly diagnosis is important in the emergency department (ED). Signs and symptoms are non-specific and radiography has low accuracy in the acute setting. Computed tomography (CT) is considered the gold standard, however it is not a cost-effective option in the vast population of patients with abdominal pain. Ultrasonography is able to detect as little as 2 ml of free air, however diagnostic accuracy of ultrasonography remains unclear. This study evaluates the accuracy of ultrasonography for the diagnosis of pneumoperitoneum, the most accurate abdominal scan and the most accurate echographic sign for the detection of free air. Methods Consecutive patients presenting to ED for acute abdominal pain and with a diagnosis of pneumoperitoneum at CT or at surgery (study group) and a similar number of patients without a diagnosis of pneumoperitoneum (control group) undergo abdominal ultrasonography in a standardized protocol that include 10 scans for each patient registered on a video of 5 seconds. The videos are randomly reviewed by 4 sonographers and by 2 physicians with no experience in ultrasonography blind to final diagnosis and to all clinical data with the aim of detecting for each scan pneumoperitoneum. Accuracy of ultrasonography for the diagnosis of pneumoperitoneum will be calculated considering CT or surgery as gold standard. Furthermore intra and interobserver agreement and the accuracy of each ultrasonographic sign and scan will be calculated.

NCT ID: NCT01956422 Completed - Clinical trials for Laparoscopy [E01.370.388.250.520]

Continuous Positive Airway Pressure (CPAP) for Preventing Respiratory Failure After Laparoscopic Radical Prostatectomy

Start date: August 2013
Phase: N/A
Study type: Interventional

Aim of this study is verify if postoperative CPAP after laparoscopic prostatectomy may reduce the impact of postoperative respiratory failure, defined as occurrence of hypoxemia (PaO2<60 mmHg) and/or reduction of Forced Expiratory Volume in 1 second (FEV1) beyond 70% of basal value.

NCT ID: NCT01930747 Completed - Muscle Relaxation Clinical Trials

Effect of Deep Neuromuscular Block (NMB), Inhalation or TIVA on Pneumoperitoneum.

TIVA
Start date: April 2013
Phase: Phase 4
Study type: Interventional

The objective of this study is to compare the value of deep neuromuscular block (NMB) (using rocuronium) in laparoscopy versus high dose opioids (using remifentanil) or 1 minimum alveolar concentration (MAC) inhalation (using sevoflurane) for the surgeon. The study hypothesis is that laparoscopic workspace is larger when using rocuronium versus opioids or inhalation. Laparoscopic workspace is measured as the abdominal compliance and the pressure at volume zero (PV0) using the abdominal pressure volume relation. Three points allow to calculate the abdominal compliance and the pressure at zero volume (PV0).

NCT ID: NCT01868347 Recruiting - Clinical trials for Obese Patients With Prostate Cancer Disease

Obese Patient During RARP: the Role of a Preemptive Ventilator Strategy to Contrast Pneumoperitoneum and Trendelenburg Position

OPERA
Start date: February 2013
Phase: Phase 3
Study type: Interventional

Analysis of the specific elastance during general anesthesia in patients treated with RARP (robotic assisted radical prostatectomy), to evaluate the efficacy of the preemptive strategy, involving recruitment maneuver and setting of 10 cmH2O PEEP before induction of pneumoperitoneum and trendelenburg position.

NCT ID: NCT01867814 Recruiting - Pneumoperitoneum Clinical Trials

Arterial and Plethysmographic Waveforms Variables as Predictors of Hemodynamic Response to Pneumoperitoneum

SPV-PnP
Start date: May 2013
Phase: N/A
Study type: Interventional

Laparoscopic surgery is frequently associated with hemodynamic changes due to pneumoperitoneum (PnP). Those complex hemodynamic changes are difficult to predict and occasionally they require active therapeutic interventions or even interruption of the surgical procedure. One of the main hemodynamic effects of PnP is a decrease in cardiac output due to reduction of venous return and cardiac preload. Although it has been shown repeatedly that waveform variables are good predictors of cardiac output response to volume loading, the prediction hemodynamic response to decrease of preload is more complex. The investigators hypothesize that waveform variables will predict cardiac output changes resulting from PnP. Particularly, augmented values of waveform variables before PnP will be associated with a larger decrease of cardiac output after establishing PnP.

NCT ID: NCT01854307 Terminated - Pneumoperitoneum Clinical Trials

The Influence of Pneumoperitoneum on Minimal Invasive Cardiac Output Measurements

Start date: May 2013
Phase: N/A
Study type: Interventional

Perioperative goal directed fluid therapy may reduce complication rate after surgery. Minimal invasive cardiac output monitoring is a key method to guide fluid therapy. More operations are being performed by keyhole surgery (laparoscopy). For laparoscopy, the abdomen is filled with carbon dioxide. Increased pressure in the abdomen may influence minimal cardiac output monitoring, therefore minimal cardiac output monitoring is not recommended during laparoscopy. This study aims to validate minimal cardiac output monitoring during laparoscopy and therefore facilitate for goal directed fluid therapy.