Pneumonia Clinical Trial
Official title:
Multicenter Osteopathic Pneumonia Study in the Elderly (MOPSE)
Osteopathic Manipulative Treatment (OMT) were used in the 1800s and 1900s to treat pneumonia before the introduction of antibiotics in the mid-1900s. The purpose of this study is to determine if OMT, when used in conjunction with antibiotics and other usual care, will improve the recovery of elderly pneumonia patients.
This study is a multi-center study conducted across five sites in the United States to
determine the efficacy of combining Osteopathic Manipulative Treatment(OMT)with antibiotics
as a treatment regimen for elderly patients with pneumonia. The study is a prospective,
randomized, controlled clinical trial, in which 360 subjects will be randomly assigned to
three different groups to test the primary hypothesis that the combination of OMT and
antibiotics will decrease the length of hospital stay for elderly patients with pneumonia.
The first group (OMT Group) will receive a series of eight osteopathic manipulative
techniques in combination with conventional antibiotic care. The second group (Light Touch
Control Group) will receive a light touch mimic treatment in combination with conventional
antibiotic care to control for the doctor-patient interaction. The third group (Conventional
Care Only Group) will receive only the conventional antibiotic care normally given to elderly
patients with pneumonia. The first two groups will receive two 15-20 minute treatments per
day, at least six hours apart, for the duration of their stay in the acute care facility.
The primary outcomes for measuring efficacy are: Length of Hospital Stay, Time to Clinical
Stability, and Rate of Symptomatic and Functional Recovery. The secondary outcomes are:
duration of IV and oral antibiotic usage in the hospital, number of complications and deaths
secondary to pneumonia, re-admission rate within 60 days of hospitalization admission date,
duration and severity of fever, duration and severity of leukocytosis, and patient
satisfaction.
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