Predictors of Outcome in Patients With Pleural Infection at Sohag University Hospital

Pleural Infection Clinical Trial

Official title:

Predictors of Outcome in Patients With Pleural Infection at Sohag University Hospital

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06141174
• Other study ID #: Soh-med-23-10-08ms
• Status: Recruiting
• Start date: November 1, 2023
• Est. completion date: May 1, 2024

Study information

• Verified date: November 2023
• Source: Sohag University
• Contact: amany e hashem, resident
• Phone: 01145694321
• Email: amanyhashem[@]med.sohag.edu.eg
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

pleural infection remains a common medical problem with significant mortality and morbidity despite a better undrstanding of the aetiology , pathophysiology and recent advances in management approaches . the cornerstones of the managment op pleural infection include early identification of cases and accurate diagnosis . suitable antibiotic therapy , nutrition managment , efficient drainage of infected collection via chest tube with or without adjunctive therapies including intrapleural agents and ultimately surgical managment .

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: May 1, 2024
• Est. primary completion date: May 1, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• patients more than 18 years old with pleural infection

Exclusion Criteria:

• hemothorax
• chest trauma within 3 month
• underwent thoracic surgery within 60 days

Related Conditions & MeSH terms

• Communicable Diseases
• Infections
• Pleural Infection

Intervention

Other:
• disease outcome ( mortality and length of stay )
insertion of intercostal tube to drain pleural collection

Locations

Country	Name	City	State
Egypt	Sohag university Hospital	Sohag

Sponsors (1)

Lead Sponsor	Collaborator
Sohag University

Country where clinical trial is conducted

Egypt, 

References & Publications (4)

Davies CW, Gleeson FV, Davies RJ; Pleural Diseases Group, Standards of Care Committee, British Thoracic Society. BTS guidelines for the management of pleural infection. Thorax. 2003 May;58 Suppl 2(Suppl 2):ii18-28. doi: 10.1136/thorax.58.suppl_2.ii18. No abstract available. — View Citation

Davies HE, Davies RJ, Davies CW; BTS Pleural Disease Guideline Group. Management of pleural infection in adults: British Thoracic Society Pleural Disease Guideline 2010. Thorax. 2010 Aug;65 Suppl 2:ii41-53. doi: 10.1136/thx.2010.137000. No abstract available. — View Citation

Gould J. Pleural infection: a case where clinical improvement was misleading. BMJ Case Rep. 2013 Apr 18;2013:bcr2013008700. doi: 10.1136/bcr-2013-008700. — View Citation

Rahman NM, Maskell NA, West A, Teoh R, Arnold A, Mackinlay C, Peckham D, Davies CW, Ali N, Kinnear W, Bentley A, Kahan BC, Wrightson JM, Davies HE, Hooper CE, Lee YC, Hedley EL, Crosthwaite N, Choo L, Helm EJ, Gleeson FV, Nunn AJ, Davies RJ. Intrapleural use of tissue plasminogen activator and DNase in pleural infection. N Engl J Med. 2011 Aug 11;365(6):518-26. doi: 10.1056/NEJMoa1012740. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	lenght of hospital stay	lenght of hospital stay since admission up to improvement	1 month
Secondary	mortality rate	mortality rate related to pleural infection	up to 30 days , 3 months