Clinical Trials Logo

Clinical Trial Summary

In this study, the possible effect of blood group distribution on the content of blood biomaterial was investigated. 64 volunteers were included in the study. Various parameters were evaluated. As a result, it was concluded that blood group distribution does not affect blood biomaterial content.


Clinical Trial Description

The aim of this split-mouth, randomized, and controlled study was to compare open flap debridement (OFD) alone against OFD with autogenous Titanium-prepared platelet-rich fibrin (OFD+ T-PRF) combined in treating intrabony defects (IBD). Subjects were 20 systemically healthy patients with chronic periodontitis according to 2017 World Workshop. Bilateral operation sites in patients (40 sites) were randomly selected for OFD alone or OFD+ T-PRF combined. Clinical parameters (probing depth (PD), relative attachment level (RAL), and gingival marginal level(GML)), radiographic parameters (intrabone defects (IBDs) and periodontal bone support (PBS)), and growth factors levels (GFL) in gingival crevicular fluid (GCF) (platelet-derived growth factors (PDGF-BB), fibroblast growth factors (FGF-2), relative ratio of receptor activator nuclear factor kappa-B (RANKL)/osteoprotegerin (OPG)) were analyzed. The Wilcoxon signed-rank test, the Student's t-test, the two way ANOVA, and the Tukey post hoc test were used for statistical analysis. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05409495
Study type Interventional
Source Ataturk University
Contact
Status Completed
Phase N/A
Start date April 1, 2021
Completion date February 15, 2022

See also
  Status Clinical Trial Phase
Completed NCT06420713 - Horizontal Bone Augmentation of Alveolar Ridge N/A
Withdrawn NCT03715439 - Evaluation of Dental Implants Placed in Preserved and Non-preserved Post-extraction Ridges
Recruiting NCT06440655 - The Efficacy and Safety of Platelet-rich Fibrin and Platelet Rich Plasma in Female Pattern Hair Loss Patients N/A
Recruiting NCT06190860 - Platelet Rich Fibrin Treatment for the Alveolar Ridge Preservation in Smokers N/A
Completed NCT05957705 - Maxillary Sinus Augmentation With Xenogeneic Bone Graft Associated or Not With Fibrin Rich in Platelets and Leukocytes Produced by Horizontal Centrifugation: A Randomized Clinical Trial. N/A
Completed NCT05264467 - Leukocyte and and Platelet-rich Fibrin Plasma for the Prevention of Anastomotic Leakage in Colorectal Anastomosis Phase 2/Phase 3
Not yet recruiting NCT06044246 - Influence of Human Platelet Derivatives on Dental Implant N/A
Active, not recruiting NCT06200727 - Platelet-rich Fibrin(PRF) Membrane in Ophthalmic Diseases N/A
Completed NCT05753631 - Effects of i-PRF on Non-surgical Periodontal Treatment
Recruiting NCT05608356 - Effect of Injectable Platelet-rich Fibrin on the En Masse Retraction of Maxillary Anterior Teeth N/A
Completed NCT05866965 - Effect of Platelet-rich Fibrin on Soft Tissue, Periodontal Pocket Healing and Alveolar Bone Height After Third Molar Surgery N/A
Completed NCT05008068 - Effect of Local Application of Platelet-rich Fibrin Scaffold Loaded With Simvastatin on Peri-implant Bone Changes Phase 1
Recruiting NCT05772975 - The Clinical Impact of E-PRF and H-PRF on Healing After Mandibular Third Molar Surgery Phase 3
Recruiting NCT05766618 - The Effect of Multiple Injections of (PRF) on The Rate of Canine Retraction Phase 3