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Effect of Injectable Platelet-rich Fibrin on the En Masse Retraction of Maxillary Anterior Teeth

Platelet-rich Fibrin Clinical Trial

Official title:
Effect of Injectable Platelet-rich Fibrin (i-PRF) on the Rate of Orthodontic En Masse Retraction of Maxillary Anterior Teeth: A Randomized Controlled Clinical Trial

Clinical Trial Summary

The aim of this study is to investigate the effect of local injection of injectable platelet rich fibrin (i-PRF) on the rate of orthodontic en masse retraction of anterior teeth clinically and to report any associated pain as well.

Clinical Trial Description

Trial will be carried on 2 groups, each involve 13 participants with a total of 26 participants. 1. Subject examination to ensure he/she meets the eligibility criteria of the research. 2. Leveling and alignment using fixed orthodontic appliance. 3. Upper first premolars extraction as a part of the orthodontic treatment planning. 4. With the starting of en masse retraction, injection of the (i-prf) obtained from venous sample palatally and distally to the anterior teeth in the intervention group, and sham injection in the control group. The injection in both groups will be done just before retraction, 21 and 42 days after beginning of retraction Rate of en masse retraction will be calculated for patients in both groups at the monthly basis for for months after starting en masse retraction, data will be analyzed statistically. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05608356
Study type Interventional
Source Cairo University
Contact Ahmed Sabrah, Master Degree of Orthodontics
Phone +201063688954
Email ahmedmagdy25291@gmail.com
Status Recruiting
Phase N/A
Start date December 1, 2022
Completion date November 30, 2023
View Details
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