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Platelet-rich Fibrin clinical trials

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NCT ID: NCT06440655 Recruiting - Clinical trials for Platelet-Rich Plasma

The Efficacy and Safety of Platelet-rich Fibrin and Platelet Rich Plasma in Female Pattern Hair Loss Patients

PRF
Start date: May 30, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare between platelet-rich fibrin and platelet-rich plasma in female pattern hair loss . The main question[s] it aims to answer are: - efficacy between platelet-rich fibrin and platelet-rich plasma - safety between platelet-rich fibrin and platelet-rich plasma Participants will be divided into 2 side of treatment with composed of 1. Platelet rich plasma 2. Platelet rich fibrin

NCT ID: NCT06190860 Recruiting - Smoking, Cigarette Clinical Trials

Platelet Rich Fibrin Treatment for the Alveolar Ridge Preservation in Smokers

Start date: May 29, 2022
Phase: N/A
Study type: Interventional

Bone healing is affected by smoking, particularly healing of extraction sockets, showing deficiencies in vertical and horizontal bone dimensions compared to the healing of non-smokers. Several approaches have been made to stimulate. Bone wound healing, including human autologous blood-derived fractions. One of these fractions is the leukocyte platelet-rich fibrin (L-PRF). L-PRF has been evidenced as potentially beneficial in promoting bone defect filling in alveolar bone and socket preservation in non-smokers. However, scarce evidence is related to this beneficial effect in smokers. This clinical trial aims to study and compare the in vivo effects of L-PRF during bone wound healing and regeneration in smokers. The main question is: Has the L-PRF a beneficial effect during alveolar ridge preservation in smokers? After consent, participants with tooth extraction indications and implant rehabilitation treatment will be enrolled. After randomization, participants will be assigned to an experimental group treated with L-PRF plugs and membranes or a control group (physiological healing). Participants will receive two interventions: - First intervention: Tooth extraction, intraoral scan, and Cone Beam Computed Tomography in the treated zone. - Second intervention (4 months after first intervention): intraoral scan and Cone Beam Computed Tomography in the treated zone

NCT ID: NCT05772975 Recruiting - Clinical trials for Platelet-Rich Fibrin

The Clinical Impact of E-PRF and H-PRF on Healing After Mandibular Third Molar Surgery

Start date: April 2023
Phase: Phase 3
Study type: Interventional

This clinical trial aims to compare the effect of platelet concentrates E-PRF and H-PRF on soft and hard tissue healing in healthy individuals after lower third molar surgery. The main questions it aims to answer are: Do E-PRF and H-PRF reduce complications after third molar surgery? Do E-PRF and H-PRF improve soft tissue healing after third molar surgery? Do E-PRF and H-PRF improve hard tissue healing after third molar surgery? Participants will be divided into 2 study groups and one control group. Third molar surgery will be performed according to standard protocol. In study groups, dentoalveolar defects will be filled with E-PRF and H-PRF which are products of centrifugation of the patient's blood without additives. Soft tissue and hard tissue healing will be compared between the groups.

NCT ID: NCT05766618 Recruiting - Orthodontics Clinical Trials

The Effect of Multiple Injections of (PRF) on The Rate of Canine Retraction

Start date: April 1, 2023
Phase: Phase 3
Study type: Interventional

this clinical trial aims to prove that multiple injections will produce a steady rate of acceleration of orthodontic tooth movement.

NCT ID: NCT05608356 Recruiting - Clinical trials for Platelet-rich Fibrin

Effect of Injectable Platelet-rich Fibrin on the En Masse Retraction of Maxillary Anterior Teeth

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effect of local injection of injectable platelet rich fibrin (i-PRF) on the rate of orthodontic en masse retraction of anterior teeth clinically and to report any associated pain as well.