Orthodontic Appliance Complication Clinical Trial
Official title:
Efficacy of Regular Home Use of Dual-light Photodynamic Therapy on Oral Health in Adolescents Undergoing Fixed Orthodontic Treatment - Randomized, Controlled Clinical Study
This study is designed to determine the efficacy of the Lumoral method on oral health in adolescents undergoing fixed orthodontic treatment. Improved supragingival plaque control can help to also sustain the subgingival plaque management in the long term. In addition, the device might have a photobiomodulation effect on periodontal tissues.
Orthodontic treatment is one of the most common dental treatments in children and adolescents. The use of fixed orthodontic appliances makes it difficult for the patients to keep their oral hygiene to an optimum level of cleanliness. Poor oral hygiene attracts significant plaque accumulation around the fixed orthodontic treatment appliances, and subsequent white spot lesions can occur rapidly, usually on the cervical and middle third of the buccal surfaces of bracketed teeth. Patients with the fixed orthodontic treatment appliances have an increased risk of caries and gingivitis. The Lumoral is a CE-marked medical device developed to provide a potent, targeted antibacterial action on dental plaque in a home environment. The device mechanism of action is antibacterial photodynamic therapy (aPDT). The device is used by swishing a mouth rinse, which has a strong adherence to dental plaque. The plaque-adhered photoactive mouth rinse can be activated by a simple to use light applicator. Preliminary results have shown a promising anti-inflammatory response in addition to plaque reduction. Forty (40) subjects undergoing fixed orthodontic treatment are randomized to the Lumoral treatment group or the control group. All subjects shall receive polishing and oral hygiene instruction. All patients shall be assessed for the clinical measurements including visible plaque index (VPI), bleeding on probing (BOP), and orthodontic plaque index (OPI) at baseline and at 4 weeks and 12 weeks after baseline. In addition, microbiological analyses shall be performed at baseline and at 12 weeks after baseline. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT03696511 -
Miniscrews Primary Stability
|
N/A | |
| Completed |
NCT05710874 -
A Prospective, Randomized, Clinical Study on the Effects of CPP-ACP-paste, Fluoride and a Combination on the Evolution of White Spot Lesions in Orthodontic Patients After Debonding.
|
N/A | |
| Completed |
NCT05818527 -
Effectiveness of Low Frequency Vibration on the Rate of Canine Retraction
|
N/A | |
| Completed |
NCT03004196 -
Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans
|
Phase 1/Phase 2 | |
| Completed |
NCT03400111 -
The Role of Paracetamol-caffeine and Laser Irradiation on Controlling Pain and Discomfort During Orthodontic Treatment
|
N/A | |
| Completed |
NCT06403033 -
Mini-implant-supported Twin-Block in Treating Patients With Class II Division 1 Malocclusion
|
N/A | |
| Active, not recruiting |
NCT05026411 -
Food Reward Circuit Change by Orthodontics
|
N/A | |
| Terminated |
NCT04604262 -
Does Use of the Waterpik Maintain Cleaner Teeth in Patients With Fixed Braces
|
N/A | |
| Completed |
NCT02427763 -
Microbiological and Epithelial Evaluation Related to the Use of Orthodontic Thermoplastic Device
|
Phase 0 | |
| Recruiting |
NCT05005689 -
Fluoride Delivery to Prevent White Spots During Orthodontic Treatment
|
Phase 4 | |
| Recruiting |
NCT04606186 -
Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodontic Treatment in Adult Patients
|
N/A | |
| Completed |
NCT05499923 -
Quantitative Measurement of ARI
|
N/A | |
| Completed |
NCT04037709 -
Photodynamic Therapy in Patients With Gingivitis
|
N/A | |
| Recruiting |
NCT04598633 -
Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodontic Treatment
|
N/A | |
| Not yet recruiting |
NCT03653078 -
Root Proximity During Mini-Screw Insertion Using a Digital Three-Dimensional Printed Guide
|
N/A | |
| Recruiting |
NCT05644119 -
Periodontal and Orthodontic Outcomes of Straight vs. Looped Fixed Retainers
|
N/A | |
| Completed |
NCT05831722 -
Changes in the Upper Airway Volume After Rapid Maxillary Expansion in Adults Using Pure Skeletal Anchorage
|
||
| Not yet recruiting |
NCT04131855 -
The Omission of Pumice Prophylaxis on Bracket Failure Rates Using Self Etch Primers
|
N/A | |
| Completed |
NCT03476161 -
Bond Failure of Two Types of Molar Buccal Tubes
|
N/A | |
| Recruiting |
NCT05733676 -
Comparison of MI Paste Plus and Resin Infiltration in White Spot Lesions Following Orthodontic Treatment
|
N/A |