Cervical Length in Cases of Placenta Previa

Placenta Previa Clinical Trial

Official title:

Value of Third Trimester Cervical Length Measurement in Predicting Risk and Severity if Antepartum Haemorrhage in Cases of Placenta Previa

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03451136
• Other study ID #: Cairo university obgyn 14534
• Status: Not yet recruiting
• Phase: N/A
• First received: February 5, 2018
• Last updated: February 28, 2018
• Start date: March 1, 2018
• Est. completion date: July 15, 2018

Study information

• Verified date: February 2018
• Source: Cairo University
• Contact: Marwa Mohamed Eid, PhD
• Phone: 01001225079
• Email: Marwameid2014[@]gmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study establishes the relationship between cervical length and whether it can be used to predict haemorrhage and preterm delivery in cases of placenta previa.

Description:

Some studies have reported an association between ultrasonographic decreased cervical length and the likelihood of complications as antepartum or post-partum haemorrhage requiring an emergency caesarean section (CS) .

The safety of trans-vaginal scanning is not in doubt, and the technique now has widespread acceptance. As a consequence, the clinical presentation of placenta previa has changed and most low lying placentas are diagnosed during the second trimester anomaly scan.

The objective of this study was to establish if there is a relation between transvaginal ultrasonographic measurement of cervical length in cases of placenta previa and whether it can be used as a predictor for antepartum haemorrhage or not.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 80
• Est. completion date: July 15, 2018
• Est. primary completion date: July 1, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 25 Years to 40 Years

Eligibility

Inclusion Criteria:

1. Age: 20-45 years old

2. Single Pregnancy

3. Fetal gestational age 28 to < 36 weeks

4. Normal amniotic fluid index (AFI)

5. Diagnosis of placenta previa by pelvic ultrasound that was confirmed when the lower placental edge overlies the internal cervical os on transvaginal ultrasound (TVS).

Exclusion Criteria:

1. Threatened preterm labor and maternal use of vaginal progesterone.

2. Preterm premature rupture of membranes;

3. Polyhydramnios;

4. Presence of cercelage and history of cervical cone biopsy which both affect cervical length.

5. Diagnosis of multiple fetal anomalies;

6. Women with other risk factors for intra-partum hemorrhage

Related Conditions & MeSH terms

• Placenta Previa

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Cervical length measured in mm in relation to antepartum haemorrhage	To find out the relationship between cervical length measured by transvaginal ultrasound and occurrence of antepartum hemorrhage in cases of placenta previa.	4 months
Secondary	Need for blood transfusion	Yes or no and no.of packed units	4 months
Secondary	Need for caesarean hysterectomy	Yes or no	4 months
Secondary	Type of cesarean delivery	Elective or emergency cesarean delivery	4 months
Secondary	Need for neonatal ICU	Yes or no	4 months