Placenta Accreta Spectrum Topographic Classification

Status Recruiting

Clinical Trial Summary

The present study is a prospective multicenter study consisting of a cohort of patients with prenatal or intraoperative diagnosis of PAS, evaluating the clinical outcomes of the group of patients found in each category of the topographic classification. In addition, an approach to evaluate the acceptability of this classification among the obstetrician-gynecologists of the participating medical centers will be included.

Clinical Trial Description

The aim of this study is to describe the demographic and clinical characteristics of patients with a diagnosis of placenta accreta spectrum, and to determine the correlation between the topographic classification and the clinical outcomes found in the study. Finally, to evaluated whether the proposed classification is accepted by the obstetrician-gynecologists of the participating centers that manage placenta accreta spectrum patients. It is an observational, multicentric study of a prospective cohort, in which data will be obtained from the medical records and other documents in each participating center, which are considered to be of routine use in day-to-day clinical practice. The study of the outcomes proposed in this protocol will be limited to those recorded in the clinical records and will be taken into account until the participant is discharged from the hospital, during which a surgical intervention was performed due to the suspicion or diagnosis of PAS. It is projected that the period of patient enrollment will last 2 years, counting on from the first participant included. The study population is pregnant patients with a diagnosis of placenta accreta spectrum who visits any of the participating medical centers, and also obstetrician-gynecologists working in participating medical centers. The centers invited to participate are hospitals or clinics that already have knowledge in how to apply the surgical staging of PAS, and the topographic classification and have experience using it. ;

Study Design

Related Conditions & MeSH terms

Placenta Accreta

Clinical Trial Details

NCT number	NCT05922397
Study type	Observational
Source	Fundacion Clinica Valle del Lili
Contact	Albaro J Nieto-Calvache, MD
Phone	6023319090
Email	albaro.nieto@fvl.org.co
Status	Recruiting
Phase
Start date	May 21, 2023
Completion date	June 1, 2025

View Details

See also
Status	Clinical Trial	Phase
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Completed	`NCT04593303` - Internal Iliac Artery Ligation During Management of Placenta Accreta Spectrum	N/A
Recruiting	`NCT03638024` - Cell-free Fetal DNA Concentration in Cases of Abnormal Placental Invasion .
Not yet recruiting	`NCT06100640` - Paracervical Pouch in Placenta Accreta Spectrum
Completed	`NCT05979181` - Peripartum Cesarean Hysterectomy for Placenta Percreta
Recruiting	`NCT04609527` - Management of Placenta Accreta Spectrum	Phase 2/Phase 3
Recruiting	`NCT06185894` - Single-step Placenta Accreta Resective Technique Tourniqueted vs Absence, Conservative Uterine Surgery	N/A
Completed	`NCT04573452` - Galectin-3 and Placenta Accreta
Not yet recruiting	`NCT03273569` - PDIUC Protocol for Placental Accreta	N/A
Completed	`NCT03707132` - Tourniquet Reduces Blood Loss in Postpartum Hemorrhage During Hysterectomy for Placenta Accreta
Not yet recruiting	`NCT05104177` - Effectivness of Conservative Techniques in Management of PAS
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Active, not recruiting	`NCT02784886` - Cell-free Fetal DNA Circulating in the Maternal Plasma as a Marker for Morbidly Adherent Placenta	N/A
Recruiting	`NCT05070689` - Placenta Accreta Spectrum Disorders: A. Chohan Continuous Squeezing Suture (ACCSS)	N/A
Completed	`NCT05813743` - Detection of Urinary Bladder Wall Involvement in Abnormally Invasive Placenta (AIP) by 3D Ultrasonography	N/A
Withdrawn	`NCT04003428` - Feasibility of HIFU for Management of Placenta Accreta (HIFU-ACCRETA)	N/A
Completed	`NCT04161521` - Conservative Surgical Novel Technique of Placenta Accreta in Menoufia University Hospital	N/A
Recruiting	`NCT05139498` - Conservative Management for PAS Pilot	N/A
Not yet recruiting	`NCT03530475` - Diagnostic Accuracy of Doppler Ultrasound and Role of Uterine Artery Doppler	N/A
Not yet recruiting	`NCT03129035` - Bilateral Internal Iliac Artery Ligation Before Cesarean Hysterectomy	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.