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NCT04082507 Clinical Trial

Maternal Serum Alpha-fetoprotein Level May Predict the Presence of Morbid Adherent Placenta

Placenta Accreta Clinical Trial

Official title:
Alpha-fetoprotein as a Biochemical Marker in Prediction of Placenta Acreta Increta Percreta

Clinical Trial Details — Status: Enrolling by invitation

Administrative data
NCT number NCT04082507
Other study ID # AFP_AP
Secondary ID
Status Enrolling by invitation
Phase
First received
Last updated
Start date January 1, 2017
Est. completion date August 30, 2019

Study information
Verified date September 2019
Source Ain Shams University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The aim of the study is to compare between alpha-fetoproteine as a biological marker and between ultrasound and Doppler in prediction of morbid adherent placenta.

Description:

in pregnant women withe previous cesarean section, placenta previa and ultrasonographic finding of an abnormally adherent placenta dose maternal serum alpha-fetoprotein predict prenataly the presence of morbid adherent placenta accurately?

Recruitment information / eligibility
Status Enrolling by invitation
Enrollment 150
Est. completion date August 30, 2019
Est. primary completion date August 30, 2019
Accepts healthy volunteers No
Gender Female
Age group 20 Years to 39 Years
Eligibility Inclusion Criteria:

- pregnant women with history of scarred uterus

- plcenta previa covering the scar of previous caesarean section as diagnosed by 2DU/S

- Gestational age from 28wks to full term

Exclusion Criteria:

- pregnant women with fetus with congenital anomalies

- pregnant women with ovarian swelling

- pregnant women with medical disease

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Serum alpha-fetoproteine
Midtrimesteric serum alpha-fetoprotein mesurment with 2D US and 3D power Doppler with MS US scan .

Locations
Country Name City State
Egypt Ain shams university maternity hospital Cairo

Sponsors (1)
Lead Sponsor Collaborator
rasha medhat abdul-hady

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary Maternal serum alpha-fetoprotein ng/ml or MOM(Multiple of the median) From 28weeks to 37 weeks
See also
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