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Pilonidal Sinus clinical trials

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NCT ID: NCT04697082 Completed - Pain Clinical Trials

Application of Platelet-rich Plasma in Pilonidal Sinus Disease

Start date: March 1, 2018
Phase: N/A
Study type: Interventional

Pilonidal sinus disease is a common health-care problem, and surgical excision is the standard treatment modality. Controversy still exists regarding the best surgical technique for treating pilonidal disease in terms of minimizing disease recurrence and patient discomfort. In this study, the investigators compared the impact of autologous platelet-rich plasma (PRP) with that of minimally invasive techniques on pain reduction, return to daily activities, quality of life, and duration of wound healing after open excision and secondary closure.

NCT ID: NCT04681443 Completed - Clinical trials for Pilonidal Sinus Without Abscess

Crystallized Phenol Treatment in Pilonidal Sinus

Start date: January 1, 2018
Phase: Phase 4
Study type: Interventional

Pilonidal sinus disease is an acquired disorder of the natal cleft and its incidence is reported as 6 in 100,000. Although there are many opinions regarding the treatment of pilonidal sinus disease in the literature, surgery is the main treatment method. Regardless of the treatment protocol, this disease has a certain risk of recurrence. Therefore, the ideal treatment procedure for the pilonidal disease should be simple to perform, should allow patients to return earlier to work, should be associated with minimal pain, and should minimize financial cost. Phenol application into the pilonidal sinus is an additional nonoperative adjunct to treatment. This method is typically used after all hair and debris have been removed or curetted from the sinus, and it helps to eliminate granulation tissue and further debris formation. The injection is followed by hair control and strict hygiene. The use of phenol causes an intense inflammatory reaction which destroys the epithelial lining, and care should be taken to protect the surrounding skin. Pain is intense and may require inpatient admission for pain control but success rates have been reported to range from 60% to 95%. However, it is difficult to know which patients can expect enough benefit from phenol application. The aim of the study is to evaluate the factors affecting the outcomes of patients with the pilonidal disease treated with crystallized phenol and to evaluate long-term recurrence rates of pilonidal disease treated with crystallized phenol.

NCT ID: NCT04599517 Completed - Pilonidal Sinus Clinical Trials

The Most Frequently Preferred Surgical Method In The Treatment Of Sacrococcygeal Pilonidal Disease

Start date: October 22, 2020
Phase:
Study type: Observational

There is no consensus on which procedure is the ideal surgical method in the treatment of sacrococcygeal pilonidal disease (SPD). The study aimed to retrospectively screen the cases that had undergone surgical treatment for SPD in the last 15 years in four different tertiary Stage hospitals and analyze the most frequently used surgical treatment method and its results.

NCT ID: NCT04572919 Completed - Pilonidal Sinus Clinical Trials

Lateral Advancement Flap Versus Classic Limberg Flap in The Treatment Of NonComplicated Pilonidal Sinus

Start date: February 1, 2017
Phase: N/A
Study type: Interventional

Background The flaps closure including natal cleft obliteration and eccentric closure are becoming more popular due to their lower rate of recurrence including both the lateral advancement adipo-fascio-cutaneous flap and the classic limberg flap. Objective This study was aim to compare the results of the surgery for non-complicated pilonidal sinus with the lateral advancement adipo-fascio-cutaneous flap versus the classic Limberg flap. Patients and methods This study was a prospective randomized controlled, and was conducted on patients with non-complicated pilonidal sinus attending Zagazig University Hospitals, Egypt during the period from February 2017 to August 2019. Patients were randomly assigned to undergo either lateral advancement flap or classic Limberg flap groups. The follow-up period ranged from 12 to 36 months. Patient satisfaction, complications and recurrence rates were analyzed and compared.

NCT ID: NCT04430413 Completed - Clinical trials for Pilonidal Disease of Natal Cleft

Effect of Platelet Rich Plasma on Healing of Operated Pilonidal Sinus by Open Method

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

The aim of the study is to assess the healing promotion effect of platelet rich plasma in patient being operated for sacrococcygeal pilonidal sinus disease by open excision

NCT ID: NCT04423510 Completed - Pilonidal Sinus Clinical Trials

Nonoperative Treatment of Recurrent Pilonidal Sinus Disease

Start date: March 1, 1995
Phase:
Study type: Observational

Postoperative recurrent pilonidal sinus disease is troublesome and its treatment is challenge. Many treatment modalities have been advocated in the treatment of recurrent pilonidal sinus disease; however, there is still no consensus in the literature. Some minimally invasive techniques are used alone or as an adjunct to surgery. Crystallized phenol is the most popular method in the nonoperative treatment of primer pilonidal sinus disease. But its long term effect in the postoperative recurrent cases is unclear. Investigators aimed to present the long-term efficacy of crystallized phenol treatment on postoperative recurrent pilonidal sinus disease through our results collected within the last 20 years.

NCT ID: NCT04356768 Completed - Pathology Clinical Trials

Histological Analysis of Sacrococcygeal Pilonidal Sinus Specimens

Start date: March 1, 2020
Phase:
Study type: Observational

Minimally invasive techniques have been widely used routinely and reliably in the treatment of pilonidal sinus. In some of these methods, the cavity of sinus remains in the patient; this condition caused us to question the necessity of pathological examination. Except for prolonged duration of disease, elderly age, macroscopic suspicion, and recurrence; We think that routine pathological examination of the pilonidal sinus is unnecessary.

NCT ID: NCT04017260 Completed - Pilonidal Sinus Clinical Trials

Combined Open and Closed Approach for Management of Pilonidal Sinus by Special U-shaped Sutures Without Drain.

Start date: December 1, 2015
Phase: N/A
Study type: Interventional

Introduction: Pilonidal sinus disease (PSD) is a common surgical disease frequently seen in the intergluteal cleft. The treatment of this problem is mainly surgical. Aim: introduce a novel technique of combined open and closed approach for management of primary pilonidal sinus (non-recurrent) by special U-shaped sutures and compare it with other techniques as regard operative time, time of complete wound healing, postoperative pain , time to stop analgesic drugs and evaluate the result of surgery without drain. Patients: this study was conducted on 160 patients with PSD in the sacrococcygeal region who underwent operation between December 2015 and December 2017. All cases are divided randomly into four groups each consists of 40 patients.

NCT ID: NCT03923621 Completed - Pilonidal Sinus Clinical Trials

Pilonidal Excision Versus Endoscopic Surgery

PEVES
Start date: March 2016
Phase: N/A
Study type: Interventional

Compare clinical outcomes of endoscopic pilonidal sinus treatment (EPSiT) with excision treatment with a randomised clinical trial.

NCT ID: NCT03765086 Completed - Pilonidal Sinus Clinical Trials

Karydakis Procedure Vs Limberg Flap in Treatment of Sacrococcygeal Pilonidal Sinus

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

This study will be a randomized controlled trial in which there will be comparison of the effectiveness of Karydakis procedure and Limberg flap in treatment of sacrococcygeal pilonidal sinus