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PIK3CA Gene Mutation clinical trials

View clinical trials related to PIK3CA Gene Mutation.

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NCT ID: NCT04976439 Completed - Colorectal Cancer Clinical Trials

Patogenic Mutation in 5 Genes

Start date: May 1, 2021
Phase:
Study type: Observational

This is a pathogenic mutation profile of colorectal patients specifically in 5 genes, i.e. APC, TP53, PIK3CA, KRAS, and MLH1. Single nucleotide variants identified were synchronized with patients' characteristics.

NCT ID: NCT04753203 Active, not recruiting - Clinical trials for Metastatic Colorectal Cancer

Alpelisib and Capecitabine in Patients With PIK3CA Mutant mCRC Patients

ALCAP
Start date: February 28, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

The investigator assesses the efficacy and safety of alpelisib and capecitabine in patients with PIK3CA mutant metastatic colorectal cancer who failed two prior standard chemotherapies.