Physical Inactivity Clinical Trial
Official title:
Targeting Cognitive Control to Improve Physical Activity Adherence in Midlife for Alzheimer's Risk Reduction
This trial is designed to develop and test the efficacy of cognitive training strategies to improve self-regulatory capacities for middle-aged adults to adopt and sustain a physically active lifestyle. The main questions it aims to answer are: - Can cognitive training designed to improve cognitive control improve physical activity adherence? - What are the psychological, physiological, cognitive, and sociodemographic factors that affect the impact of cognitive control on physical activity adherence? Participants will - Complete a 6-week home-based, computerized cognitive training program - Complete a 6-week home-based, aerobic exercise training program with supervision of a health coach and trainer - Complete a 6-week home-based, aerobic exercise training program prescribed by a health coach and trainer - Visit the laboratory before and after cognitive training, and before and after physical training, to complete assessments of cognition and aerobic fitness
Participants will first be screened to ensure eligibility for participating in moderate to vigorous intensity exercise based on health history and approval from their primary physician or equivalent. Participants will then complete pre-testing and a three-phased intervention. Pre-intervention sessions include study screening, cognitive testing, physical activity assessment, and sub-maximal cardiorespiratory fitness testing. Participants will then be randomized into one of three cognitive training programs for a 6-week cognitive training intervention. The cognitive training program includes 15 hours of progressive adaptive training. Participants complete 30 min of training 5 days a week to complete a dose of 15 hours of cognitive training. A minimum of 10 hours of completed cognitive training is needed to progress to the exercise training program. Upon completion of cognitive training, participants will complete testing to assess changes in cognitive function, and then be enrolled in a two-phase exercise intervention. The 12-week exercise program includes a first 6-week introductory and fully supervised training program that builds towards meeting the minimum suggested exercise per week for long-term health benefits (150 minutes/week of moderate intensity exercise). Following the first 6 weeks, participants will be prescribed a maintenance program to be completed fully at home with their heart rate monitor from the study team, and with safety monitoring from our exercise specialist. After completing the second 6-week exercise intervention, participants will again complete the cognitive and cardiorespiratory fitness testing they did during pre-intervention sessions. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT05659862 -
Digitally Assisted Behavioral Physical Activity Intervention in Fibromyalgia
|
N/A | |
| Recruiting |
NCT05294692 -
Using Behavioural Economics for More Sustainable Physical Activity mHealth Incentives: the Caterpillar App
|
N/A | |
| Recruiting |
NCT05619250 -
Supervised Center-based vs. Unsupervised Home-based Exercise Programs (PRO-Training)
|
N/A | |
| Recruiting |
NCT06088485 -
The Effect of Bone Mineral Density in Patients With Adult Cystic Fibrosis
|
||
| Not yet recruiting |
NCT05963893 -
Promoting a Healthy Life Through Gender Equity
|
||
| Enrolling by invitation |
NCT05461989 -
Physical Activity Barriers in Adolescent Hypertension Patients
|
||
| Completed |
NCT06063187 -
Technology-based Fall Risk Assessments for Older Adults in Low-income Settings
|
||
| Active, not recruiting |
NCT06089876 -
The Use of Mobile Applications in Obese and Overweight Adolescents for Health Improvement
|
N/A | |
| Recruiting |
NCT05608707 -
APPETITE: Plant Protein and Exercise Solutions for the Prevention of Undernutrition in Older Adults.
|
N/A | |
| Enrolling by invitation |
NCT06033417 -
Walking and Blood Pressure in Older Adults With Respiratory Impairment.
|
N/A | |
| Not yet recruiting |
NCT05887583 -
Supporting Physical Literacy at School and Home
|
N/A | |
| Completed |
NCT05535400 -
Effects of Physical-Psychological Integrative Intervention on SCI Patient: a Pilot Randomized Controlled Trial
|
N/A | |
| Recruiting |
NCT06095999 -
Perfect Fit: Evaluation of a Virtual Coach for Smoking Cessation and Physical Activity
|
N/A | |
| Completed |
NCT06246812 -
Text Message and Competition-Based Interventions Among University Students
|
N/A | |
| Recruiting |
NCT05935982 -
Virtual Reality Exercise in a Community Highschool for Children With Disabilities
|
Phase 1 | |
| Not yet recruiting |
NCT06027502 -
Cardioprotective Benefit of Passive Heat Therapy in Higher-Level Spinal Cord Injury: Safety and Proof of Concept
|
N/A | |
| Recruiting |
NCT05147909 -
Impact of Dietary Phosphate Excess on Exercise Capacity and Visceral Adiposity
|
N/A | |
| Recruiting |
NCT06185413 -
Children's Cooperation Denmark: a 3-year System Dynamics Trial
|
N/A | |
| Completed |
NCT06018974 -
Digital Gaming Intervention for Older People in Long-term Care
|
N/A | |
| Recruiting |
NCT05425641 -
MoST-Influenced Behavioral Intervention for Walking
|
Phase 2 |