The Effect of Exercise on Ovarian Reserve

Status Not yet recruiting

Clinical Trial Summary

The purpose of this study is to examine how different levels of physical activity impact the ovarian reserve during the pre-menopausal period

Clinical Trial Description

Two groups are included:

1. The study group: women between 20-35 years of age who practice high level of physical activity, as defined by International Physical Activity Questionnaire , for the past 3 years

2. The control group: women between 20-35 years of age who practice low level of physical activity, as defined by International Physical Activity Questionnaire , for the past 3 years

Women who meet the criteria for inclusion for will be recruited to the study after signing a consent form. Recruitment will be done through sport centers. The control group will include women being examined in gynecologic emergency department, after signing a consent form, if they meet the control group's inclusion criteria. These women will be asked to fulfill the International Physical Activity Questionnaire and additional questionnaire regarding relevant demographic and medical information (see below). Blood samples to anti-mullerian hormone , leptin, and hormonal profile will be obtained in day 3 of menstruation. Ultrasound will be performed to measure Antral Follicular count and ovarian blood flow.

Data collection:

1. Demographic information on age, weight, height, BMI, marital status

2. Medical information regarding chronic diseases and medications

3. Obstetrical history

4. Information regarding physical activities in the version of International Physical Activity Questionnaire .

5. Information about menstrual behavior: irregularity (yes/no) frequency (less than 21 days between 21-35 days, over 35 days), menstrual duration (less than 3 days 3-7 days, or over 7 days) bleeding amount according to the number of pads per day (up to 1, 2, 4 or 5 pads).

6. Hormonal profile - Follicle-stimulating hormone , Luteinizing hormone , progesterone, Estradiol, Thyroid-stimulating hormone .

7. Antral Follicle Count, Anti-mullerian hormone

8. Leptin levels -reflecting metabolic changes. ;

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Physical Exercise

Clinical Trial Details

NCT number	NCT02999568
Study type	Observational
Source	Meir Medical Center
Contact	Amir Wiser, MD
Phone	07297472901
Email	Amir.Wiser@clalit.org.il
Status	Not yet recruiting
Phase	N/A
Start date	February 2017
Completion date	August 2019

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT04439097` - Effects of Multicomponent Physical Exercise Program and Mediterranean Diet in Alzheimer's Disease	N/A
Completed	`NCT04612127` - Efficacy of the Consumption of a Spinach Extract on Muscle Function in Subjects Over 50 Years of Age	N/A
Completed	`NCT05938634` - A Randomized Controlled Trial Using Stage-matched Intervention Based on the Transtheoretical Model of Change to Enhance Engaging in Regular Physical Exercise Among High School Female Students.	N/A
Recruiting	`NCT06091384` - Inspiratory Muscle Strength Training in Post-Covid Syndrome	N/A
Enrolling by invitation	`NCT04651140` - Research on the Effect and Mechanism of Aerobic Exercise on PD	N/A
Completed	`NCT04251611` - Randomized Clinical Trial by Conglomerates on the Efficacy of Maintenance of Physical Exercise in Myocardial Ischemia	N/A
Completed	`NCT03415880` - Light Intensity Physical Activity Trial	N/A
Active, not recruiting	`NCT05698472` - A Study on the Status Quo of Physical Exercise for the Elderly
Completed	`NCT04345237` - Changes in Body Composition When Ingesting a Dairy Compound Enriched With Leucine	N/A
Not yet recruiting	`NCT04822896` - Acute Effects of Motor Imagery and Physical Exercise on Tongue Strength and Pain Threshold in Healthy Adults	N/A
Recruiting	`NCT06270667` - Effects of Exercise Training in Survivors of Lymphoma	N/A
Recruiting	`NCT06370546` - Cardiac Response to Strength Training in Hypertensive Individuals	N/A
Completed	`NCT03385837` - Activity Level and Barriers to Participate of Cardiac Rehabilitation in Advanced Heart Failure Patients
Recruiting	`NCT05910814` - Effect of Physical Exercise on Motor Learning Acquired With Physical or Mental Practice	N/A
Completed	`NCT04024280` - Effects of a Physical Exercise Program in Quality of Life of Breast Cancer Survivors	N/A
Completed	`NCT03517293` - Enhanced Neonatal Health and Neonatal Cardiac Effect Developmentally	N/A
Recruiting	`NCT05726474` - Comparison of the Effect of Two Types of Physical Exercises in Patients With Heart Failure With Preserved Ejection Fraction	N/A
Completed	`NCT04243174` - The Use of Short SMS Messaging With Type 2 Diabetes (T2DM)	N/A
Terminated	`NCT04234009` - Lifestyle and Brain Vascular Function	N/A
Recruiting	`NCT04506840` - Physical Activity and Motivation in Colorectal Cancer Patients	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.